Now showing items 1-4 of 4

    • Determinants of protection among HIV‐exposed seronegative persons: an overview. 

      Alter, G; Anthony, D; Carrington, Mary; Cho, M; Daskalakis, DC; Douek, DC; Goedert, JJ; ... (16 authors) (J Infect Dis, 2010-11-01)
      Both clinical experience and a growing medical literature indicate that some persons who have been exposed to human immunodeficiency virus (HIV) infection remain uninfected. Although in some instances this may represent ...
    • Influence of HLA-C expression level on HIV control. 

      Apps, R; Bosch, R; Brumme, CJ; Brumme, ZL; Buchbinder, S; Carlson, JM; Carrington, Mary; ... (37 authors) (Science, 2013-04-05)
      A variant upstream of human leukocyte antigen C (HLA-C) shows the most significant genome-wide effect on HIV control in European Americans and is also associated with the level of HLA-C expression. We characterized ...
    • Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. 

      Center for HIV/AIDS Vaccine Immunology (CHAVI); Cirulli Rogers, Elizabeth T; Ge, Dongliang; Goedert, JJ; Goldstein, David Benjamin; Heinzen, EL; Maia, JM; ... (10 authors) (Genome Biol, 2010)
      BACKGROUND: There is considerable interest in the development of methods to efficiently identify all coding variants present in large sample sets of humans. There are three approaches possible: whole-genome sequencing, ...
    • The characterization of twenty sequenced human genomes. 

      Campbell, CR; Cirulli Rogers, Elizabeth T; Dickson, SP; Fellay, J; Ge, Dongliang; Goedert, JJ; Goldstein, David Benjamin; ... (25 authors) (PLoS Genet, 2010-09-09)
      We present the analysis of twenty human genomes to evaluate the prospects for identifying rare functional variants that contribute to a phenotype of interest. We sequenced at high coverage ten "case" genomes from individuals ...