Browsing by Author "Guinney, Justin"

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    • The Geometry of Cancer 

      Guinney, Justin (2009)
      Cancer is a complex, multifaceted disease that operates through dynamic changes in the genome. Cancer is best understood through the process that generates it -- random mutations operated on by natural selection -- and ...

    • The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution. 

      Rozenblatt-Rosen, Orit; Regev, Aviv; Oberdoerffer, Philipp; Nawy, Tal; Hupalowska, Anna; Rood, Jennifer E; Ashenberg, Orr; ... (38 authors) (Cell, 2020-04)
      Crucial transitions in cancer-including tumor initiation, local expansion, metastasis, and therapeutic resistance-involve complex interactions between cells within the dynamic tumor ecosystem. Transformative single-cell ...