Now showing items 1-2 of 2

    • Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes. 

      Abrahams, BS; Alvarez Retuerto, AI; Bradfield, JP; Bucan, M; Buxbaum, JD; Cantor, RM; Cook, EH; ... (36 authors) (PLoS Genet, 2009-06)
      The genetics underlying the autism spectrum disorders (ASDs) is complex and remains poorly understood. Previous work has demonstrated an important role for structural variation in a subset of cases, but has lacked the resolution ...
    • Rare variants create synthetic genome-wide associations. 

      Dickson, SP; Goldstein, David Benjamin; Hakonarson, H; Krantz, I; Wang, K (PLoS Biol, 2010-01-26)
      Genome-wide association studies (GWAS) have now identified at least 2,000 common variants that appear associated with common diseases or related traits (http://www.genome.gov/gwastudies), hundreds of which have been convincingly ...