Now showing items 1-6 of 6

    • Analytical performance evaluation of the Elecsys® Troponin T Gen 5 STAT assay. 

      Fitzgerald, Robert L; Hollander, Judd E; Peacock, W Frank; Limkakeng, Alexander T; Breitenbeck, Nancy; Blechschmidt, Kareen; Laimighofer, Michael; ... (8 authors) (Clinica chimica acta; international journal of clinical chemistry, 2019-08)
      BACKGROUND:We report the analytical performance of the Elecsys® Troponin T Gen 5 STAT (TnT Gen 5 STAT; Roche Diagnostics) assay. METHODS:Measuring limits/ranges were determined in lithium-heparin plasma samples per Clinical ...
    • Efficacy of High-Sensitivity Troponin T in Identifying Very-Low-Risk Patients With Possible Acute Coronary Syndrome. 

      Peacock, W Frank; Baumann, Brigette M; Bruton, Deborah; Davis, Thomas E; Handy, Beverly; Jones, Christopher W; Hollander, Judd E; ... (12 authors) (JAMA cardiology, 2018-02)
      Importance:Physicians need information on how to use the first available high-sensitivity troponin (hsTnT) assay in the United States to identify patients at very low risk for 30-day adverse cardiac events (ACE). Objective:To ...
    • Emergency physician high pretest probability for acute coronary syndrome correlates with adverse cardiovascular outcomes. 

      Chandra, Abhinav; Lindsell, Christopher J; Limkakeng, Alexander; Diercks, Deborah B; Hoekstra, James W; Hollander, Judd E; Kirk, J Douglas; ... (11 authors) (Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009-08)
      OBJECTIVES: The value of unstructured physician estimate of risk for disease processes, other than acute coronary syndrome (ACS), has been demonstrated. The authors sought to evaluate the predictive value of unstructured ...
    • International, multicenter evaluation of a new D-dimer assay for the exclusion of venous thromboembolism using standard and age-adjusted cut-offs. 

      Parry, Blair Alden; Chang, Anna Marie; Schellong, Sebastian M; House, Stacey L; Fermann, Gregory J; Deadmon, Erin K; Giordano, Nicholas J; ... (30 authors) (Thrombosis research, 2018-04-05)
      We sought to determine the test characteristics of an automated INNOVANCE D-dimer assay for the exclusion of pulmonary embolism (PE) and deep venous thrombosis (DVT) in emergency department (ED) patients using standard and ...
    • The 99th percentile upper reference limit for the 5th generation cardiac troponin T assay in the United States. 

      Fitzgerald, Robert L; Hollander, Judd E; Peacock, W Frank; Limkakeng, Alexander T; Breitenbeck, Nancy; Rivers, E Joy; Ziegler, André; ... (9 authors) (Clinica chimica acta; international journal of clinical chemistry, 2020-05)
      BACKGROUND:Determining diagnostic thresholds for cardiac troponin assays is key to interpreting their clinical performance. We describe the calculation of 99th percentile upper reference limits (URLs) for the Elecsys® Troponin ...
    • Using Sex-specific Cutoffs for High-sensitivity Cardiac Troponin T to Diagnose Acute Myocardial Infarction. 

      Peacock, W Frank; Baumann, Brigitte M; Rivers, E Joy; Davis, Thomas E; Handy, Beverly; Jones, Christopher W; Hollander, Judd E; ... (13 authors) (Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2020-07-29)
      High-sensitivity cardiac troponin (hs-cTn) assays facilitate early decision-making in acute myocardial infarction (AMI).1 The accuracy of these assays now allow sex-specific differences in levels to be detected within healthy ...