Browsing by Author "Howard, Jason T"
Now showing items 1-12 of 12
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A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes.
(Proc Natl Acad Sci U S A, 2006-10-10)Songbirds have one of the most accessible neural systems for the study of brain mechanisms of behavior. However, neuroethological studies in songbirds have been limited by the lack of high-throughput molecular resources ... -
Comparative genomics reveals insights into avian genome evolution and adaptation.
(Science, 2014-12-12)Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian species representing all major extant clades. ... -
Convergent differential regulation of SLIT-ROBO axon guidance genes in the brains of vocal learners.
(J Comp Neurol, 2015-04-15)Only a few distantly related mammals and birds have the trait of complex vocal learning, which is the ability to imitate novel sounds. This ability is critical for speech acquisition and production in humans, and is attributed ... -
Convergent transcriptional specializations in the brains of humans and song-learning birds.
(Science, 2014-12-12)Song-learning birds and humans share independently evolved similarities in brain pathways for vocal learning that are essential for song and speech and are not found in most other species. Comparisons of brain transcriptomes ... -
Core and region-enriched networks of behaviorally regulated genes and the singing genome.
(Science, 2014-12-12)Songbirds represent an important model organism for elucidating molecular mechanisms that link genes with complex behaviors, in part because they have discrete vocal learning circuits that have parallels with those that ... -
High-coverage sequencing and annotated assemblies of the budgerigar genome.
(Gigascience, 2014)BACKGROUND: Parrots belong to a group of behaviorally advanced vertebrates and have an advanced ability of vocal learning relative to other vocal-learning birds. They can imitate human speech, synchronize their body movements ... -
Hybrid error correction and de novo assembly of single-molecule sequencing reads.
(Nat Biotechnol, 2012-07-01)Single-molecule sequencing instruments can generate multikilobase sequences with the potential to greatly improve genome and transcriptome assembly. However, the error rates of single-molecule reads are high, which has limited ... -
Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species.
(Elife, 2013-09-03)Cells are fundamental units of life, but little is known about evolution of cell states. Induced pluripotent stem cells (iPSCs) are once differentiated cells that have been re-programmed to an embryonic stem cell-like state, ... -
Phylogenomic analyses data of the avian phylogenomics project.
(Gigascience, 2015)BACKGROUND: Determining the evolutionary relationships among the major lineages of extant birds has been one of the biggest challenges in systematic biology. To address this challenge, we assembled or collected the genomes ... -
Sequencing three crocodilian genomes to illuminate the evolution of archosaurs and amniotes.
(Genome Biol, 2012-01-31)The International Crocodilian Genomes Working Group (ICGWG) will sequence and assemble the American alligator (Alligator mississippiensis), saltwater crocodile (Crocodylus porosus) and Indian gharial (Gavialis gangeticus) ... -
Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs.
(Science, 2014-12-12)To provide context for the diversification of archosaurs--the group that includes crocodilians, dinosaurs, and birds--we generated draft genomes of three crocodilians: Alligator mississippiensis (the American alligator), ... -
Whole-genome analyses resolve early branches in the tree of life of modern birds.
(Science, 2014-12-12)To better determine the history of modern birds, we performed a genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves using phylogenomic methods created to handle genome-scale data. We recovered ...
