Browsing by Author "Huang, Bofu"

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Metabolic Control of CaMKII-mediated Caspase-2 Suppression by B55β/PP2A

Huang, Bofu (2015)

Apoptosis is a programmed form of cell death, essential for maintaining tissue homeostasis and eliminating dysfunctional cells. The process of apoptosis is executed by a family of cysteine proteases called caspases. High ...
Suppression of DNA-damage checkpoint signaling by Rsk-mediated phosphorylation of Mre11.

Chen, Chen; Zhang, Liguo; Huang, Nai-Jia; Huang, Bofu; Kornbluth, Sally (Proc Natl Acad Sci U S A, 2013-12-17)

Ataxia telangiectasia mutant (ATM) is an S/T-Q-directed kinase that is critical for the cellular response to double-stranded breaks (DSBs) in DNA. Following DNA damage, ATM is activated and recruited by the MRN protein complex ...