Browsing by Author "Hughes, Claude L"
Now showing items 1-9 of 9
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Alcohol, drugs, caffeine, tobacco, and environmental contaminant exposure: reproductive health consequences and clinical implications.
(Critical reviews in toxicology, 2010-08)Reproductive function and fertility are thought to be compromised by behaviors such as cigarette smoking, substance abuse, and alcohol consumption; however, the strength of these associations are uncertain. Furthermore, ... -
Application of the estrogen threshold hypothesis to the physiologic hypoestrogenemia of lactation.
(Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 2015-03)OBJECTIVE: This study determined the impact of breastfeeding on hypoestrogenic symptoms among women in the postpartum period and correlated these findings with the Estrogen Threshold Hypothesis, which postulates that the ... -
Black cohosh increases metastatic mammary cancer in transgenic mice expressing c-erbB2.
(Cancer research, 2008-10)Black cohosh is an herbal extract that is often used as an alternative to estrogen-based replacement therapies to treat hot flushes that frequently accompany the transition to menopause. Although cancer-free women as well ... -
Gene expression in oogenesis and implications for transgenerational effects of environmental toxicants.
(Biology of reproduction, 2011-01) -
Inhibition of Neu-induced mammary carcinogenesis in transgenic mice expressing ERΔ3, a dominant negative estrogen receptor α variant.
(Hormones & cancer, 2012-12)The estrogen receptor α (ERα) splicing variant with an in-frame deletion of exon 3 (ERΔ3) is frequently expressed in the normal breast, but its influence on tumorigenesis has not been explored. In vitro, ERΔ3 has dominant ... -
Interactions between life stress factors and carrying the APOE4 allele adversely impact self-reported health in old adults.
(The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2011-10)Based on the multiple logistic regression analysis of data from a random sample of 1,023 old adults collected in Taiwan in 2000, we found that interactions between carrying the APOE4 allele and one of four life stress factors ... -
Modeling endocrine control of the pituitary-ovarian axis: androgenic influence and chaotic dynamics.
(Bulletin of mathematical biology, 2014-01)Mathematical models of the hypothalamus-pituitary-ovarian axis in women were first developed by Schlosser and Selgrade in 1999, with subsequent models of Harris-Clark et al. (Bull. Math. Biol. 65(1):157-173, 2003) and Pasteur ... -
Pre-birth acquisition of personhood: Incremental accrual of attributes as the framework for individualization by serial and concurrently acting developmental factors.
(Frontiers in reproductive health, 2023-01)Discrete events and processes influence development of individual humans. Attribution of personhood to any individual human being cannot be disconnected from the underlying biological events and processes of early human ... -
The Impact of Endometriosis on the Health of Women.
(BioMed research international, 2015-01)
