Browsing by Author "Iba, Toshiaki"

COVID-19: Thrombosis, thromboinflammation, and anticoagulation considerations.

Levy, Jerrold H; Iba, Toshiaki; Olson, Lyra B; Corey, Kristen M; Ghadimi, Kamrouz; Connors, Jean M (International journal of laboratory hematology, 2021-07)

Vascular endothelial injury is a hallmark of acute infection at both the microvascular and macrovascular levels. The hallmark of SARS-CoV-2 infection is the current COVID-19 clinical sequelae of the pathophysiologic responses ...

Diagnosis and management of sepsis-induced coagulopathy and disseminated intravascular coagulation.

Iba, Toshiaki; Levy, Jerrold H; Warkentin, Theodore E; Thachil, Jecko; van der Poll, Tom; Levi, Marcel; Scientific and Standardization Committee on DIC, and the Scientific and Standardization Committee on Perioperative and Critical Care of the International Society on Thrombosis and Haemostasis (Journal of thrombosis and haemostasis : JTH, 2019-07-20)

Thrombomodulin in disseminated intravascular coagulation and other critical conditions-a multi-faceted anticoagulant protein with therapeutic potential.

Ito, Takashi; Thachil, Jecko; Asakura, Hidesaku; Levy, Jerrold H; Iba, Toshiaki (Critical care (London, England), 2019-08-15)

Thrombomodulin plays a vital role in maintaining intravascular patency due to its anticoagulant, antiinflammatory, and cytoprotective properties. However, under pathological conditions such as sepsis and systemic inflammation, ...