Browsing by Author "Jeune, Bernard"
Now showing items 1-10 of 10
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Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals.
(Exp Gerontol, 2014-09)Gene variants found to associate with human longevity in one population rarely replicate in other populations. The lack of consistent findings may partly be explained by genetic heterogeneity among long-lived individuals ... -
Changes in hospitalisation and surgical procedures among the oldest-old: a follow-up study of the entire Danish 1895 and 1905 cohorts from ages 85 to 99 years.
(Age Ageing, 2013-07)OBJECTIVE: to examine whether the Danish 1905 cohort members had more active hospital treatment than the 1895 cohort members from ages 85 to 99 years and whether it results in higher in-hospital and post-operative mortality. ... -
Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: two nationwide cohort studies.
(Aging Cell, 2010-12)Studies of Nordic twins suggest an increased genetic influence on mortality with age. Contrary to this, the heterogeneity hypothesis predicts that the mortality of individuals carrying a 'frail' or 'risky' genotype in a ... -
[More people live to be very old and with a better functioning].
(Ugeskr Laeger, 2013-10-07)Death rates for 80+-year-olds are now half of what they were after WWII. The chance of living past 90 years has gone up by roughly 30% per decade for people born in Denmark in 1895, 1905, and 1915 - and the later cohorts ... -
Optimism and survival: does an optimistic outlook predict better survival at advanced ages? A twelve-year follow-up of Danish nonagenarians.
(Aging Clin Exp Res, 2013-10)BACKGROUND AND AIMS: Studies examining predictors of survival among the oldest-old have primarily focused on objective measures, such as physical function and health status. Only a few studies have examined the effect of ... -
Physical and cognitive functioning of people older than 90 years: a comparison of two Danish cohorts born 10 years apart.
(Lancet, 2013-11-02)BACKGROUND: A rapidly increasing proportion of people in high-income countries are surviving into their tenth decade. Concern is widespread that the basis for this development is the survival of frail and disabled elderly ... -
Physical and mental decline and yet rather happy? A study of Danes aged 45 and older.
(Aging Ment Health, 2015)OBJECTIVES: Little is known about whether the feeling of happiness follows the age-related decline in physical and mental functioning. The objective of this study was to analyze differences with age in physical and mental ... -
Rise, stagnation, and rise of Danish women's life expectancy.
(Proc Natl Acad Sci U S A, 2016-04-12)Health conditions change from year to year, with a general tendency in many countries for improvement. These conditions also change from one birth cohort to another: some generations suffer more adverse events in childhood, ... -
Survival Prognosis in Very Old Adults.
(J Am Geriatr Soc, 2016-01)OBJECTIVES: To determine whether simple functional indicators are predictors of survival prognosis in very old adults. DESIGN: In-person survey conducted over a 3-month period in 1998; assessment of survival over a 15-year ...
