Now showing items 1-2 of 2

    • Liver regeneration requires Yap1-TGFβ-dependent epithelial-mesenchymal transition in hepatocytes. 

      Oh, Seh-Hoon; Swiderska-Syn, Marzena; Jewell, Mark L; Premont, Richard T; Diehl, Anna Mae (Journal of hepatology, 2018-05-11)
      Chronic failure of mechanisms that promote effective regeneration of dead hepatocytes causes replacement of functional hepatic parenchyma with fibrous scar and ultimately results in cirrhosis. Therefore, defining and optimizing ...
    • Loss of pericyte smoothened activity in mice with genetic deficiency of leptin. 

      Xie, Guanhua; Swiderska-Syn, Marzena; Jewell, Mark L; Machado, Mariana Verdelho; Michelotti, Gregory A; Premont, Richard T; Diehl, Anna Mae (BMC Cell Biol, 2017-04-20)
      BACKGROUND: Obesity is associated with multiple diseases, but it is unclear how obesity promotes progressive tissue damage. Recovery from injury requires repair, an energy-expensive process that is coupled to energy availability ...