Browsing by Author "Johnson, G Allan"

A Diffusion MRI Tractography Connectome of the Mouse Brain and Comparison with Neuronal Tracer Data.

Badea, Alexandra; Calabrese, Evan; Cofer, Gary P; Johnson, G Allan; Qi, Y (Cereb Cortex, 2015-11)

Interest in structural brain connectivity has grown with the understanding that abnormal neural connections may play a role in neurologic and psychiatric diseases. Small animal connectivity mapping techniques are particularly ...

A LabVIEW Platform for Preclinical Imaging Using Digital Subtraction Angiography and Micro-CT.

Badea, CT; Hedlund, Laurence W; Johnson, G Allan (J Med Eng, 2013)

CT and digital subtraction angiography (DSA) are ubiquitous in the clinic. Their preclinical equivalents are valuable imaging methods for studying disease models and treatment. We have developed a dual source/detector X-ray ...

Altered diffusion tensor imaging measurements in aged transgenic Huntington disease rats.

Antonsen, BT; Jiang, Y; Johnson, G Allan; Leergaard, TB; Nguyen, HP; Qu, H; Sijbers, J; ... (9 authors) (Brain Struct Funct, 2013-05)

Rodent models of Huntington disease (HD) are valuable tools for investigating HD pathophysiology and evaluating new therapeutic approaches. Non-invasive characterization of HD-related phenotype changes is important for monitoring ...

Assessing cardiac injury in mice with dual energy-microCT, 4D-microCT, and microSPECT imaging after partial heart irradiation.

Badea, CT; Befera, N; Clark, D; Das, S; Johnson, G Allan; Kirsch, David Guy; Lee, CL; ... (9 authors) (Int J Radiat Oncol Biol Phys, 2014-03-01)

PURPOSE: To develop a mouse model of cardiac injury after partial heart irradiation (PHI) and to test whether dual energy (DE)-microCT and 4-dimensional (4D)-microCT can be used to assess cardiac injury after PHI to complement ...

Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate.

Ament, JJ; Budin, F; Cofer, Gary P; Everson, JL; Holloway, HT; Johnson, G Allan; Lipinski, RJ; ... (10 authors) (PLoS One, 2014)

Subtle behavioral and cognitive deficits have been documented in patient cohorts with orofacial clefts (OFCs). Recent neuroimaging studies argue that these traits are associated with structural brain abnormalities but have ...

Computed tomography imaging of primary lung cancer in mice using a liposomal-iodinated contrast agent.

Annapragada, A; Athreya, KK; Badea, CT; Clark, D; Espinosa, G; Ghafoori, AP; Ghaghada, KB; ... (10 authors) (PLoS One, 2012)

PURPOSE: To investigate the utility of a liposomal-iodinated nanoparticle contrast agent and computed tomography (CT) imaging for characterization of primary nodules in genetically engineered mouse models of non-small cell ...

High-resolution reconstruction of fluorescent inclusions in mouse thorax using anatomically guided sampling and parallel Monte Carlo computing.

Badea, Cristian Tudorel; Hood, G; Johnson, G Allan; Qi, Y; Stiles, J; Wetzel, A; Zhang, X (Biomed Opt Express, 2011-09-01)

We present a method for high-resolution reconstruction of fluorescent images of the mouse thorax. It features an anatomically guided sampling method to retrospectively eliminate problematic data and a parallel Monte Carlo ...

Localization of Metal Electrodes in the Intact Rat Brain Using Registration of 3D Microcomputed Tomography Images to a Magnetic Resonance Histology Atlas.

Badea, Alexandra; Badea, Cristian Tudorel; Borg, JS; Dzirasa, Kafui; Johnson, G Allan; Vu, MA (eNeuro, 2015-07)

Simultaneous neural recordings taken from multiple areas of the rodent brain are garnering growing interest due to the insight they can provide about spatially distributed neural circuitry. The promise of such recordings ...