Browsing by Author "Johnson, G Allan"
Now showing items 1-12 of 12
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A Diffusion MRI Tractography Connectome of the Mouse Brain and Comparison with Neuronal Tracer Data.
(Cereb Cortex, 2015-11)Interest in structural brain connectivity has grown with the understanding that abnormal neural connections may play a role in neurologic and psychiatric diseases. Small animal connectivity mapping techniques are particularly ... -
A LabVIEW Platform for Preclinical Imaging Using Digital Subtraction Angiography and Micro-CT.
(J Med Eng, 2013)CT and digital subtraction angiography (DSA) are ubiquitous in the clinic. Their preclinical equivalents are valuable imaging methods for studying disease models and treatment. We have developed a dual source/detector X-ray ... -
Altered diffusion tensor imaging measurements in aged transgenic Huntington disease rats.
(Brain Struct Funct, 2013-05)Rodent models of Huntington disease (HD) are valuable tools for investigating HD pathophysiology and evaluating new therapeutic approaches. Non-invasive characterization of HD-related phenotype changes is important for monitoring ... -
Assessing cardiac injury in mice with dual energy-microCT, 4D-microCT, and microSPECT imaging after partial heart irradiation.
(Int J Radiat Oncol Biol Phys, 2014-03-01)PURPOSE: To develop a mouse model of cardiac injury after partial heart irradiation (PHI) and to test whether dual energy (DE)-microCT and 4-dimensional (4D)-microCT can be used to assess cardiac injury after PHI to complement ... -
Characterization complex collagen fiber architecture in knee joint using high-resolution diffusion imaging.
(Magnetic resonance in medicine, 2020-01-21)PURPOSE:To evaluate the complex fiber orientations and 3D collagen fiber network of knee joint connective tissues, including ligaments, muscle, articular cartilage, and meniscus using high spatial and angular resolution ... -
Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate.
(PLoS One, 2014)Subtle behavioral and cognitive deficits have been documented in patient cohorts with orofacial clefts (OFCs). Recent neuroimaging studies argue that these traits are associated with structural brain abnormalities but have ... -
Ex Vivo MR Histology and Cytometric Feature Mapping Connect Three-dimensional in Vivo MR Images to Two-dimensional Histopathologic Images of Murine Sarcomas.
(Radiology. Imaging cancer, 2021-05)Purpose To establish a platform for quantitative tissue-based interpretation of cytoarchitecture features from tumor MRI measurements. Materials and Methods In a pilot preclinical study, multicontrast in vivo MRI of murine ... -
Localization of Metal Electrodes in the Intact Rat Brain Using Registration of 3D Microcomputed Tomography Images to a Magnetic Resonance Histology Atlas.
(eNeuro, 2015-07)Simultaneous neural recordings taken from multiple areas of the rodent brain are garnering growing interest due to the insight they can provide about spatially distributed neural circuitry. The promise of such recordings ... -
Magnetic resonance imaging of graded skeletal muscle injury in live rats.
(Environ Health Insights, 2014)INTRODUCTION: Increasing number of stretch-shortening contractions (SSCs) results in increased muscle injury. METHODS: Fischer Hybrid rats were acutely exposed to an increasing number of SSCs in vivo using a custom-designed ... -
Magnetic resonance microscopy.
(Anal Cell Pathol (Amst), 2012) -
MRI tools for assessment of microstructure and nephron function of the kidney.
(Am J Physiol Renal Physiol, 2016-12-01)MRI can provide excellent detail of renal structure and function. Recently, novel MR contrast mechanisms and imaging tools have been developed to evaluate microscopic kidney structures including the tubules and glomeruli. ... -
Quantitative mapping of trimethyltin injury in the rat brain using magnetic resonance histology.
(Neurotoxicology, 2014-05)The growing exposure to chemicals in our environment and the increasing concern over their impact on health have elevated the need for new methods for surveying the detrimental effects of these compounds. Today's gold standard ...
