Browsing by Author "Kabiraj, Parijat"

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Site-specific phosphorylation and caspase cleavage of GFAP are new markers of Alexander disease severity.

Battaglia, Rachel A; Beltran, Adriana S; Delic, Samed; Dumitru, Raluca; Robinson, Jasmine A; Kabiraj, Parijat; Herring, Laura E; ... (16 authors) (eLife, 2019-11-04)

Alexander disease (AxD) is a fatal neurodegenerative disorder caused by mutations in glial fibrillary acidic protein (GFAP), which supports the structural integrity of astrocytes. Over 70 GFAP missense mutations cause AxD, ...