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Browsing by Author "Khan, Muhammad Shahzeb"
Now showing items 1-10 of 10
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Association Between Obesity and Cardiovascular Outcomes: A Systematic Review and Meta-analysis of Mendelian Randomization Studies.
(JAMA network open, 2018-11-02)Importance:Although dyslipidemia has been consistently shown to be associated with atherogenesis, an association between obesity and cardiovascular disease outcomes remains controversial. Mendelian randomization can minimize ... -
Conflicts of Interest and Outcomes of Cardiovascular Trials.
(Am J Cardiol, 2016-03-01)Conflicts of interests have long been recognized as potential sources of influence in the conduct and reporting of clinical trials. This controversy was again rekindled after the publication of the latest statin guidelines ... -
Evaluation of Industrial Compensation to Cardiologists in 2015.
(Am J Cardiol, 2017-12-15)The categorization and characterization of pharmaceutical and device manufacturers or group purchasing organization payments to clinicians is an important step toward assessing conflicts of interest and the potential impact ... -
Impact of Funding Source on Clinical Trial Results Including Cardiovascular Outcome Trials.
(Am J Cardiol, 2015-12-15)Previous authors have suggested a higher likelihood for industry-sponsored (IS) studies to have positive outcomes than non-IS studies, though the influence of publication bias was believed to be a likely confounder. We attempted ... -
Is Anticoagulation Beneficial in Pulmonary Arterial Hypertension?
(Circulation. Cardiovascular quality and outcomes, 2018-09)Background Data about anticoagulation in pulmonary arterial hypertension (PAH) patients are inconsistent. The objective of this study was to examine the impact of adjunctive oral anticoagulants in patients with PAH through ... -
Mapping 123 million neonatal, infant and child deaths between 2000 and 2017.
(Nature, 2019-10-16)Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2-to end preventable ... -
Meta-analysis of Placebo-Controlled Randomized Controlled Trials on the Prevalence of Statin Intolerance.
(Am J Cardiol, 2017-09-01)The prevalence of intolerance varies widely. Stopping statin therapy is associated with worse outcomes in patients with cardiovascular disease. Despite extensive studies, the benefits and risks of statins continue to be ... -
Novel oral anticoagulants versus vitamin K antagonists in patients with atrial fibrillation after transcatheter aortic valve replacement: A systematic review and meta-analysis.
(Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2022-04-27)<h4>Background</h4>The efficacy and safety of novel oral anticoagulants (NOACs) compared to the current guideline-recommended vitamin K antagonists (VKAs) in atrial fibrillation (AF) patients undergoing transcatheter aortic ... -
Safety and Use of Anticoagulation After Aortic Valve Replacement With Bioprostheses: A Meta-Analysis.
(Circ Cardiovasc Qual Outcomes, 2016-05)BACKGROUND: The American College of Cardiology guidelines recommend 3 months of anticoagulation after replacement of the aortic valve with a bioprosthesis. However, there remains great variability in the current clinical ... -
Transcatheter closure of patent foramen ovale following cryptogenic stroke: An updated meta-analysis of randomized controlled trials.
(American heart journal, 2018-05)Transcatheter closure of patent foramen ovale (PFO) after cryptogenic stroke has long been a contentious issue. Herein, we pool aggregate data examining safety and efficacy of transcatheter closure of PFO compared with medical ...
