Browsing by Author "Knight, Julian C"
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A community approach to mortality prediction in sepsis via gene expression analysis.
Sweeney, Timothy E; Perumal, Thanneer M; Henao, Ricardo; Nichols, Marshall; Howrylak, Judith A; Choi, Augustine M; Bermejo-Martin, Jesús F; ... (26 authors) (Nature communications, 2018-02)Improved risk stratification and prognosis prediction in sepsis is a critical unmet need. Clinical severity scores and available assays such as blood lactate reflect global illness severity with suboptimal performance, and ... -
Sepsis Subclasses: A Framework for Development and Interpretation.
DeMerle, Kimberley M; Angus, Derek C; Baillie, J Kenneth; Brant, Emily; Calfee, Carolyn S; Carcillo, Joseph; Chang, Chung-Chou H; ... (30 authors) (Critical care medicine, 2021-05)Sepsis is defined as a dysregulated host response to infection that leads to life-threatening acute organ dysfunction. It afflicts approximately 50 million people worldwide annually and is often deadly, even when evidence-based ...