Browsing by Author "Kurhanewicz, Nicole"
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Nutritional control of mRNA isoform expression during developmental arrest and recovery in C. elegans.
Maxwell, Colin S; Antoshechkin, Igor; Kurhanewicz, Nicole; Belsky, Jason A; Baugh, L Ryan (Genome Res, 2012-10)Nutrient availability profoundly influences gene expression. Many animal genes encode multiple transcript isoforms, yet the effect of nutrient availability on transcript isoform expression has not been studied in genome-wide ... -
Pol II docking and pausing at growth and stress genes in C. elegans.
Maxwell, Colin S; Kruesi, William S; Core, Leighton J; Kurhanewicz, Nicole; Waters, Colin T; Lewarch, Caitlin L; Antoshechkin, Igor; ... (10 authors) (Cell Rep, 2014-02-13)Fluctuations in nutrient availability profoundly impact gene expression. Previous work revealed postrecruitment regulation of RNA polymerase II (Pol II) during starvation and recovery in Caenorhabditis elegans, suggesting ... -
Sensitive and precise quantification of insulin-like mRNA expression in Caenorhabditis elegans.
Baugh, L Ryan; Kurhanewicz, Nicole; Sternberg, Paul W (PLoS One, 2011-03-22)Insulin-like signaling regulates developmental arrest, stress resistance and lifespan in the nematode Caenorhabditis elegans. However, the genome encodes 40 insulin-like peptides, and the regulation and function of individual ...