Browsing by Author "Kurtzberg, J"
Now showing items 1-20 of 24
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A novel reduced-intensity conditioning regimen for unrelated umbilical cord blood transplantation in children with nonmalignant diseases
(Biology of Blood and Marrow Transplantation, 2014)Reduced-intensity conditioning (RIC) regimens have the potential to decrease transplantation-related morbidity and mortality. However, engraftment failure has been prohibitively high after RIC unrelated umbilical cord blood ... -
Allogeneic hematopoietic SCT for alpha-mannosidosis: an analysis of 17 patients.
(Bone marrow transplantation, 2012-03)Alpha-mannosidosis is a rare lysosomal storage disease. Hematopoietic SCT (HSCT) is usually recommended as a therapeutic option though reports are anecdotal to date. This retrospective multi institutional analysis describes ... -
Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring
(International Journal of Obesity, 2013)Objectives: Low birth weight (LBW) has been associated with common adult-onset chronic diseases, including obesity, cardiovascular disease, type II diabetes and some cancers. The etiology of LBW is multi-factorial. However, ... -
Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring.
(International journal of obesity (2005), 2013-07)<h4>Objectives</h4>Low birth weight (LBW) has been associated with common adult-onset chronic diseases, including obesity, cardiovascular disease, type II diabetes and some cancers. The etiology of LBW is multi-factorial. ... -
Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements.
(Epigenetics : official journal of the DNA Methylation Society, 2012-07)Depressed mood in pregnancy has been linked to low birth weight (LBW, 4,500 g) infants had 5.9% higher methylation at the PLAGL1 DMR compared with normal birth weight infants. Our findings confirm that severe maternal depressed ... -
Durable Chimerism and Long-Term Survival Following Unrelated Umbilical Cord Blood Transplantation for Pediatric Hemophagocytic Lymphohistiocytosis: a Single Center Experience
(Biology of Blood and Marrow Transplantation, 2017-10) -
Effect of maternal obesity on Maternal-Fetal transfer of preoperative cefazolin at cesarean section
(Journal of Pediatric Pharmacology and Therapeutics, 2017-05-01)OBJECTIVES American Congress of Obstetricians and Gynecologists recommends a single dose of antibiotic prophylaxis before all cesarean sections (C/S). This recommendation is based on pharmacokinetic studies that include ... -
Extensive haplotype diversity in African American mothers and their cord blood units.
(Tissue antigens, 2013-01)HLA-A, -B, -C, -DRB1, -DQB1 assignments were obtained for 374 pairs of African American mothers and their umbilical cord blood units (CBU) by DNA sequencing. An algorithm developed by the National Marrow Donor Program was ... -
Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilical-cord blood from an HLA-identical sibling
(Cellular Therapy and Transplantation, 2010-12-01)The clinical manifestations of Fanconi's anemia, an autosomal recessive disorder, include progressive pancyto-penia, a predisposition to neoplasia, and nonhematopoietic developmental anomalies [1-3]. Hypersensitivity to ... -
In reply.
(Transfusion, 2014-02) -
Massive clonal expansion of medulloblastoma-specific T cells during adoptive cellular therapy.
(Science advances, 2019-11-27)In both human and murine systems, we have developed an adoptive cellular therapy platform against medulloblastoma and glioblastoma that uses dendritic cells pulsed with a tumor RNA transcriptome to expand polyclonal ... -
MYELOABLATIVE (MAC) AUTOLOGOUS STEM-CELL TRANSPLANTATION (AUTOSCT) FOLLOWED BY REDUCED INTENSITY (RIC) ALLOGENEIC STEM-CELL TRANSPLANTATION (ALLOSCT) IN CHILDREN, ADOLESCENTS, AND YOUNG ADULTS (CAYA) WITH POOR RISK HODGKIN LYMPHOMA (HL): INDUCTION OF LONG-TERM GVHL EFFECT
(PEDIATRIC BLOOD & CANCER, 2011-05-01) -
Newborns of obese parents have altered DNA methylation patterns at imprinted genes
(International Journal of Obesity, 2015-04-09)Background:Several epidemiologic studies have demonstrated associations between periconceptional environmental exposures and health status of the offspring in later life. Although these environmentally related effects have ... -
Newborns of obese parents have altered DNA methylation patterns at imprinted genes.
(International journal of obesity (2005), 2015-04)Several epidemiologic studies have demonstrated associations between periconceptional environmental exposures and health status of the offspring in later life. Although these environmentally related effects have been attributed ... -
Pre-engraftment syndrome after myeloablative dual umbilical cord blood transplantation: risk factors and response to treatment.
(Bone marrow transplantation, 2013-07)High fevers and/or rashes prior to neutrophil engraftment are frequently observed after umbilical cord blood (UCB) transplantation, and the condition is referred to as pre-engraftment syndrome (PES). Few studies have evaluated ... -
Rapid and efficient generation of transgene-free iPSC from a small volume of cryopreserved blood
(Stem Cell Reviews and Reports, 2015)© The Author(s) 2015.Human peripheral blood and umbilical cord blood represent attractive sources of cells for reprogramming to induced pluripotent stem cells (iPSCs). However, to date, most of the blood-derived iPSCs were ...
