Browsing by Author "Lantos, Paul M"
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A Systematic Review of Borrelia burgdorferi Morphologic Variants Does Not Support a Role in Chronic Lyme Disease
Lantos, Paul M; Auwaerter, Paul G; Wormser, Gary P (Clinical Infectious Diseases, 2013-12-12)Background. Much of the controversy that surrounds Lyme disease pertains to whether it produces prolonged, treatment-refractory infection, usually referred to as chronic Lyme disease. Some have proposed that round morphologic ... -
Bartonella vinsonii subsp. berkhoffii and Bartonella henselae bacteremia in a father and daughter with neurological disease
Breitschwerdt, Edward B; Maggi, Ricardo G; Lantos, Paul M; Woods, Christopher W; Hegarty, Barbara C; Bradley, Julie M (2010)Background: Bartonella vinsonii subsp. berkhoffii is an important, emerging, intravascular bacterial pathogen that has been recently isolated from immunocompetent patients with endocarditis, arthritis, neurological disease ... -
Chronic coinfections in patients diagnosed with chronic lyme disease: a systematic review.
Lantos, Paul M; Wormser, Gary P (Am J Med, 2014-11)PURPOSE: Often, the controversial diagnosis of chronic Lyme disease is given to patients with prolonged, medically unexplained physical symptoms. Many such patients also are treated for chronic coinfections with Babesia, ... -
Chronic Lyme disease.
Lantos, Paul M (Infect Dis Clin North Am, 2015-06)Chronic Lyme disease is a poorly defined diagnosis that is usually given to patients with prolonged, unexplained symptoms or with alternative medical diagnoses. Data do not support the proposition that chronic, ... -
Chronic Lyme disease: the controversies and the science.
Lantos, Paul M (Expert Rev Anti Infect Ther, 2011-07)The diagnosis of chronic Lyme disease has been embroiled in controversy for many years. This is exacerbated by the lack of a clinical or microbiologic definition, and the commonality of chronic symptoms in the general population. ... -
Detection of Bartonella species in the blood of veterinarians and veterinary technicians: a newly recognized occupational hazard?
Lantos, Paul M; Maggi, Ricardo G; Ferguson, Brandy; Varkey, Jay; Park, Lawrence P; Breitschwerdt, Edward B; Woods, Christopher W (Vector Borne Zoonotic Dis, 2014-08)BACKGROUND: Bartonella species are important emerging pathogens in human and veterinary medicine. In the context of their daily activities, veterinary professionals have frequent animal contact and arthropod exposures. Detection ... -
Empiric antibiotic treatment of erythema migrans-like skin lesions as a function of geography: a clinical and cost effectiveness modeling study.
Lantos, Paul M; Brinkerhoff, R Jory; Wormser, Gary P; Clemen, Robert (Vector Borne Zoonotic Dis, 2013-12)The skin lesion of early Lyme disease, erythema migrans (EM), is so characteristic that routine practice is to treat all such patients with antibiotics. Because other skin lesions may resemble EM, it is not known whether ... -
Final report of the Lyme disease review panel of the Infectious Diseases Society of America.
Lantos, Paul M; Charini, William A; Medoff, Gerald; Moro, Manuel H; Mushatt, David M; Parsonnet, Jeffrey; Sanders, John W; ... (8 authors) (Clin Infect Dis, 2010-07-01)In April 2008, the Infectious Diseases Society of America (IDSA) entered into an agreement with Connecticut Attorney General Richard Blumenthal to voluntarily undertake a special review of its 2006 Lyme disease guidelines. ... -
Geographic and Racial Disparities in Infant Hearing Loss.
Lantos, Paul M; Maradiaga-Panayotti, Gabriela; Barber, Xavier; Raynor, Eileen; Tucci, Debara; Hoffman, Kate; Permar, Sallie R; ... (11 authors) (Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2018-10-09)Objective Approximately 1 to 2 of every 1000 American newborns has hearing loss identified by newborn screening. This study was designed to determine if infant hearing loss is more common in socioeconomically disadvantaged ... -
Geographic expansion of Lyme disease in Michigan, 2000-2014
Lantos, Paul M; Tsao, Jean; Nigrovic, Lise E; Auwaerter, Paul G; Fowler, Vance G; Ruffin, Felicia; Foster, Erik; ... (8 authors) (Open Forum Infectious Diseases, 2017-01-01)© The Author 2017.Background. Most Lyme disease cases in the Midwestern United States are reported in Minnesota and Wisconsin. In recent years, however, a widening geographic extent of Lyme disease has been noted with evidence ... -
Geographic Expansion of Lyme Disease in the Southeastern United States, 2000-2014.
Lantos, Paul M; Nigrovic, Lise E; Auwaerter, Paul G; Fowler, Vance G; Ruffin, Felicia; Brinkerhoff, R Jory; Reber, Jodi; ... (11 authors) (Open Forum Infect Dis, 2015-12)Background. The majority of Lyme disease cases in the United States are acquired on the east coast between northern Virginia and New England. In recent years the geographic extent of Lyme disease has been expanding, raising ... -
Heterogeneity in the Effectiveness of Non-pharmaceutical Interventions During the First SARS-CoV2 Wave in the United States.
Pan, William K; Fernández, Daniel; Tyrovolas, Stefanos; Iago, Giné-Vázquez; Dasgupta, Rishav Raj; Zaitchik, Benjamin F; Lantos, Paul M; ... (8 authors) (Frontiers in public health, 2021-01)Background: Attempts to quantify effect sizes of non-pharmaceutical interventions (NPI) to control COVID-19 in the US have not accounted for heterogeneity in social or environmental factors that may influence NPI effectiveness. ... -
Lyme Disease Serology.
Lantos, Paul M; Auwaerter, Paul G; Nelson, Christina A (JAMA, 2016-04-26) -
Lyme disease vaccination: are we ready to try again?
Lantos, Paul M (Lancet Infect Dis, 2013-08) -
Lyme disease: authentic imitator or wishful imitation?
Melia, Michael T; Lantos, Paul M; Auwaerter, Paul G (JAMA Neurol, 2014-10) -
Neighborhood Disadvantage is Associated with High Cytomegalovirus Seroprevalence in Pregnancy.
Lantos, Paul M; Hoffman, Kate; Permar, Sallie R; Jackson, Pearce; Hughes, Brenna L; Kind, Amy; Swamy, Geeta (J Racial Ethn Health Disparities, 2017-08-24)BACKGROUND: Cytomegalovirus (CMV) is the most common infectious cause of fetal malformations and childhood hearing loss. CMV is more common among socially disadvantaged groups, and geographically clusters in poor communities. ... -
Racial, Ethnic, and Geographic Disparities in Novel Coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2) Test Positivity in North Carolina.
Turner, Nicholas A; Pan, William; Martinez-Bianchi, Viviana S; Panayotti, Gabriela M Maradiaga; Planey, Arrianna M; Woods, Christopher W; Lantos, Paul M (Open forum infectious diseases, 2021-01)<h4>Background</h4>Emerging evidence suggests that black and Hispanic communities in the United States are disproportionately affected by coronavirus disease 2019 (COVID-19). A complex interplay of socioeconomic and healthcare ... -
Rickettsia rickettsii transmission by a lone star tick, North Carolina.
Breitschwerdt, Edward B; Hegarty, Barbara C; Maggi, Ricardo G; Lantos, Paul M; Aslett, Denise M; Bradley, Julie M (Emerg Infect Dis, 2011-05)Only indirect or circumstantial evidence has been published to support transmission of Rickettsia rickettsii by Amblyomma americanum (lone star) ticks in North America. This study provides molecular evidence that A. americanum ... -
The Excess Burden of Cytomegalovirus in African American Communities: A Geospatial Analysis.
Lantos, Paul M; Permar, Sallie R; Hoffman, Kate; Swamy, Geeta K (Open Forum Infect Dis, 2015-12)Background. Cytomegalovirus (CMV) is a common cause of birth defects and hearing loss in infants and opportunistic infections in the immunocompromised. Previous studies have found higher CMV seroprevalence rates among minorities ... -
The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children.
Lipsett, Susan C; Pollock, Nira R; Branda, John A; Gordon, Caroline D; Gordon, Catherine R; Lantos, Paul M; Nigrovic, Lise E (Pediatr Infect Dis J, 2015-11)By using a Lyme enzyme-linked immunosorbent assay (ELISA), we demonstrated that high ELISA index values are strongly predictive of Lyme disease. In children with clinical presentations consistent with Lyme disease, ELISA ...