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Browsing by Author "Le, Thuy"
Now showing items 1-20 of 37
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A Trial of Itraconazole or Amphotericin B for HIV-Associated Talaromycosis.
Le, Thuy; Kinh, Nguyen Van; Cuc, Ngo TK; Tung, Nguyen LN; Lam, Nguyen T; Thuy, Pham TT; Cuong, Do D; ... (25 authors) (N Engl J Med, 2018-03-16)BACKGROUND: Talaromyces marneffei infection is a major cause of human immunodeficiency virus (HIV)-related death in South and Southeast Asia. Guidelines recommend initial treatment with amphotericin B deoxycholate, but this ... -
AIDS-associated Penicillium marneffei infection of the central nervous system.
Le, Thuy; Huu Chi, Nguyen; Kim Cuc, Ngo T; Manh Sieu, Tran Phu; Shikuma, Cecilia M; Farrar, Jeremy; Day, Jeremy N (Clin Infect Dis, 2010-12-15)Penicillium marneffei is an important human immunodeficiency virus-associated opportunistic infection endemic in Southeast Asia. Central nervous system infection has not been described. We report the first case series of ... -
AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection: a therapeutic dilemma in resource‐limited settings.
Le, Thuy; Hong Chau, Tran Thi; Kim Cuc, Ngo Thi; Si Lam, Pham; Manh Sieu, Tran Phu; Shikuma, Cecilia M; Day, Jeremy N (Clin Infect Dis, 2010-11-01)AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection has not been adequately studied and poses unique therapeutic challenges in resource‐limited settings. Itraconazole poorly penetrates ... -
Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.
Axfors, Cathrine; Schmitt, Andreas M; Janiaud, Perrine; Van't Hooft, Janneke; Abd-Elsalam, Sherief; Abdo, Ehab F; Abella, Benjamin S; ... (94 authors) (Nature communications, 2021-05-14)The original version of this Article contained an error in the spelling of the author Muhammad Shahzad, which was incorrectly given as Muhammad Shehzad. This has now been corrected in both the PDF and HTML versions of the ... -
Complete genome sequences for two talaromyces marneffei clinical isolates from Northern and Southern Vietnam
Cuomo, Christina A; Shea, Terrance; Nguyen, Thu; Ashton, Philip; Perfect, John; Le, Thuy (Microbiology Resource Announcements, 2020-01-01)© 2020 Cuomo et al. Talaromyces marneffei is a thermally dimorphic fungus endemic in China and Southeast Asia that causes fatal infections in immunocompromised individuals, particularly in patients with advanced HIV disease. ... -
Cost-Effectiveness of Amphotericin B Deoxycholate Versus Itraconazole for Induction Therapy of Talaromycosis in Human Immunodeficiency Virus-Infected Adults in Vietnam.
Buchanan, James; Altunkaya, James; Van Kinh, Nguyen; Van Vinh Chau, Nguyen; Trieu Ly, Vo; Thi Thanh Thuy, Pham; Hai Vinh, Vu; ... (14 authors) (Open forum infectious diseases, 2021-07-05)<h4>Background</h4>Talaromycosis (penicilliosis) is an invasive fungal infection and a major cause of human immunodeficiency virus (HIV)-related deaths in Southeast Asia. Guidelines recommend induction therapy with amphotericin ... -
COVID-19 Trials: Who Participates and Who Benefits?
Narayanasamy, Shanti; Mourad, Ahmad; Turner, Nicholas A; Le, Thuy; Rolfe, Robert J; Okeke, Nwora Lance; O'Brien, Sean M; ... (13 authors) (Southern medical journal, 2022-04)<h4>Objectives</h4>The coronavirus disease 2019 (COVID-19) pandemic has disproportionately afflicted vulnerable populations. Older adults, particularly residents of nursing facilities, represent a small percentage of the ... -
Detection and Characterization of Human Pegivirus 2, Vietnam.
Anh, Nguyen To; Hong, Nguyen Thi Thu; Nhu, Le Nguyen Truc; Thanh, Tran Tan; Anscombe, Catherine; Chau, Le Ngoc; Thanh, Tran Thi Thanh; ... (18 authors) (Emerging infectious diseases, 2018-11)We report human pegivirus 2 (HPgV-2) infection in Vietnam. We detected HPgV-2 in some patients with hepatitis C virus/HIV co-infection but not in patients with HIV or hepatitis A, B, or C virus infection, nor in healthy ... -
Development and evaluation of a real-time polymerase chain reaction assay for the rapid detection of Talaromyces marneffei MP1 gene in human plasma
Hien, Ha Thuc Ai; Thanh, Tran Tan; Thu, Nguyen Thi Mai; Nguyen, Ashley; Thanh, Nguyen Tat; Lan, Nguyen Phu Huong; Simmons, Cameron; ... (11 authors) (Mycoses, 2016-12-01)© 2016 The Authors. Mycoses Published by Blackwell Verlag GmbH Penicilliosis caused by Talaromyces marneffei is a common AIDS-defining illness in South and Southeast Asia. Diagnosis is based on culture which can take up ... -
Diagnosing Rhodococcus equi infections in a setting where tuberculosis is highly endemic: a double challenge.
Le, Thuy; Cash-Goldwasser, Shama; Tho, Phan Vinh; Lan, Nguyen Phu Huong; Campbell, James I; van Doorn, H Rogier; Lam, Nguyen Tien; ... (11 authors) (J Clin Microbiol, 2015-04)Rhodococcus equi infection is increasing in regions with high HIV prevalence worldwide. The microbiological features and clinical mimicry of tuberculosis infection pose diagnostic challenges in high-tuberculosis-incidence ... -
Diagnosis and Management of Systemic Endemic Mycoses Causing Pulmonary Disease
Salzer, Helmut JF; Burchard, Gerd; Cornely, Oliver A; Lange, Christoph; Rolling, Thierry; Schmiedel, Stefan; Libman, Michael; ... (11 authors) -
Differential prevalence and geographic distribution of hepatitis C virus genotypes in acute and chronic hepatitis C patients in Vietnam.
Le Ngoc, Chau; Tran Thi Thanh, Thanh; Tran Thi Lan, Phuong; Nguyen Mai, Trinh; Nguyen Hoa, Trang; Nghiem My, Ngoc; Le Van, Tan; ... (18 authors) (PloS one, 2019-01)BACKGROUND:The highest burden of disease from hepatitis C virus (HCV) is found in Southeast Asia, but our understanding of the epidemiology of infection in many heavily burdened countries is still limited. In particular, ... -
Effect of mutations in Pneumocystis carinii dihydropteroate synthase gene on outcome of P carinii pneumonia in patients with HIV-1: a prospective study
Navin, Thomas R; Beard, Charles B; Huang, Laurence; del Rio, Carlos; Lee, Sherline; Pieniazek, Norman J; Carter, Jane L; ... (10 authors) (The Lancet, 2001-08) -
Effects of cotrimoxazole prophylaxis on Talaromyces marneffei infection in HIV/AIDS patients receiving antiretroviral therapy: a retrospective cohort study
Jiang, Junjun; Qin, Fengxiang; Meng, Sirun; Nehl, Eric J; Huang, Jinping; Liu, Yanfen; Zou, Jun; ... (23 authors) (Emerging Microbes & Infections, 2019-01) -
Environmental predictors and incubation period of AIDS-associated penicillium marneffei infection in Ho Chi Minh City, Vietnam.
Bulterys, Philip L; Le, Thuy; Quang, Vo Minh; Nelson, Kenrad E; Lloyd-Smith, James O (Clin Infect Dis, 2013-05)BACKGROUND: Penicillium marneffei is an emerging dimorphic mycosis endemic in Southeast Asia, and a leading cause of mortality among human immunodeficiency virus (HIV)-infected people in the region. Factors governing the ... -
Epidemiology, seasonality, and predictors of outcome of AIDS-associated Penicillium marneffei infection in Ho Chi Minh City, Viet Nam.
Le, Thuy; Wolbers, Marcel; Chi, Nguyen Huu; Quang, Vo Minh; Chinh, Nguyen Tran; Lan, Nguyen Phu Huong; Lam, Pham Si; ... (11 authors) (Clin Infect Dis, 2011-04-01)BACKGROUND: Penicillium marneffei is an important human immunodeficiency virus (HIV)-associated opportunistic pathogen in Southeast Asia. The epidemiology and the predictors of penicilliosis outcome are poorly understood. ... -
Fungal infections in HIV/AIDS.
Limper, Andrew H; Adenis, Antoine; Le, Thuy; Harrison, Thomas S (Lancet Infect Dis, 2017-11)Fungi are major contributors to the opportunistic infections that affect patients with HIV/AIDS. Systemic infections are mainly with Pneumocystis jirovecii (pneumocystosis), Cryptococcus neoformans (cryptococcosis), Histoplasma ... -
Global guideline for the diagnosis and management of the endemic mycoses: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology.
Thompson, George R; Le, Thuy; Chindamporn, Ariya; Kauffman, Carol A; Alastruey-Izquierdo, Ana; Ampel, Neil M; Andes, David R; ... (39 authors) (The Lancet. Infectious diseases, 2021-12)The global burden of the endemic mycoses (blastomycosis, coccidioidomycosis, emergomycosis, histoplasmosis, paracoccidioidomycosis, sporotrichosis, and talaromycosis) continues to rise yearly and these infectious diseases ... -
High prevalence of PI resistance in patients failing second-line ART in Vietnam.
Thao, Vu Phuong; Quang, Vo Minh; Day, Jeremy N; Chinh, Nguyen Tran; Shikuma, Cecilia M; Farrar, Jeremy; Van Vinh Chau, Nguyen; ... (10 authors) (J Antimicrob Chemother, 2016-03)BACKGROUND: There are limited data from resource-limited settings on antiretroviral resistance mutations that develop in patients failing second-line PI ART. METHODS: We performed a cross-sectional virological assessment ... -
HIV-1 drug resistance in antiretroviral-naive individuals with HIV-1-associated tuberculous meningitis initiating antiretroviral therapy in Vietnam.
Thao, Vu P; Le, Thuy; Török, Estee M; Yen, Nguyen TB; Chau, Tran TH; Jurriaans, Suzanne; van Doorn, H Rogier; ... (10 authors) (Antivir Ther, 2012)BACKGROUND: Access to antiretroviral therapy (ART) for HIV-infected individuals in Vietnam is rapidly expanding, but there are limited data on HIV drug resistance (HIVDR) to guide ART strategies. METHODS: We retrospectively ...