Browsing by Author "Lee, Patty J"

Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.

Katsura, Hiroaki; Sontake, Vishwaraj; Tata, Aleksandra; Kobayashi, Yoshihiko; Edwards, Caitlin E; Heaton, Brook E; Konkimalla, Arvind; ... (16 authors) (Cell stem cell, 2020-10-21)

Coronavirus infection causes diffuse alveolar damage leading to acute respiratory distress syndrome. The absence of ex vivo models of human alveolar epithelium is hindering an understanding of coronavirus disease 2019 (COVID-19) ...

Immuno-fibrotic drivers of impaired lung function in post-COVID-19 syndrome.

Chun, Hyung J; Coutavas, Elias; Pine, Alexander; Lee, Alfred I; Yu, Vanessa; Shallow, Marcus; Giovacchini, Coral X; ... (12 authors) (medRxiv, 2021-02-06)

Introduction: Subjects recovering from COVID-19 frequently experience persistent respiratory ailments; however, little is known about the underlying biological factors that may direct lung recovery and the extent to which ...

Immunofibrotic drivers of impaired lung function in postacute sequelae of SARS-CoV-2 infection.

Chun, Hyung J; Coutavas, Elias; Pine, Alexander B; Lee, Alfred I; Yu, Vanessa L; Shallow, Marcus K; Giovacchini, Coral X; ... (12 authors) (JCI insight, 2021-07-22)

BACKGROUNDIndividuals recovering from COVID-19 frequently experience persistent respiratory ailments, which are key elements of postacute sequelae of SARS-CoV-2 infection (PASC); however, little is known about the underlying ...