Browsing by Author "Lee, Sang Hyun"

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    • BUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression. 

      Xu, Peng; Raetz, Elizabeth A; Kitagawa, Mayumi; Virshup, David M; Lee, Sang Hyun (Biol Open, 2013-05-15)
      BUBR1 is a mitotic phosphoprotein essential for the maintenance of chromosome stability by promoting chromosome congression and proper kinetochore-microtubule (K-fiber) attachment, but the underlying mechanism(s) has remained ...

    • CoA synthase regulates mitotic fidelity via CBP-mediated acetylation. 

      Lin, Chao-Chieh; Kitagawa, Mayumi; Tang, Xiaohu; Hou, Ming-Hsin; Wu, Jianli; Qu, Dan Chen; Srinivas, Vinayaka; ... (13 authors) (Nature communications, 2018-03-12)
      The temporal activation of kinases and timely ubiquitin-mediated degradation is central to faithful mitosis. Here we present evidence that acetylation controlled by Coenzyme A synthase (COASY) and acetyltransferase ...