Browsing by Author "Li, Wei"
Now showing items 1-14 of 14
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Association between increased magnetic susceptibility of deep gray matter nuclei and decreased motor function in healthy adults.
(Neuroimage, 2015-01-15)In the human brain, iron is more prevalent in gray matter than in white matter, and deep gray matter structures, particularly the globus pallidus, putamen, caudate nucleus, substantia nigra, red nucleus, and dentate nucleus, ... -
Associations between genetic variants of KIF5B, FMN1, and MGAT3 in the cadherin pathway and pancreatic cancer risk.
(Cancer medicine, 2020-11-16)Because the cadherin-mediated signaling pathway promotes cancer progression, we assessed associations between genetic variants in 109 cadherin-related genes and risk of pancreatic cancer (PanC) by using genotyping data from ... -
Associations of novel variants in PIK3C3, INSR and MAP3K4 of the ATM pathway genes with pancreatic cancer risk.
(American journal of cancer research, 2020-01)The ATM serine/threonine kinase (ATM) pathway plays important roles in pancreatic cancer (PanC) development and progression, but the roles of genetic variants of the genes in this pathway in the etiology of PanC are unknown. ... -
Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis.
(Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021-10)Colorectal cancer (CRC) metastasizes mainly to the liver, which accounts for the majority of CRC-related deaths. Here it is shown that metastatic cells undergo specific chromatin remodeling in the liver. Hepatic growth factor ... -
Costs and Benefits Associated With Transradial Versus Transfemoral Percutaneous Coronary Intervention in China.
(Journal of the American Heart Association, 2016-04-22)Transradial percutaneous coronary intervention (PCI) has been increasingly adopted in clinical practice, given its potential advantages over transfemoral intervention; however, the impact of different access strategies on ... -
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Human Brain Mapping, 2014-06)As indicated by several recent studies, magnetic susceptibility of the brain is influenced mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination and iron deposition in the brain evolve ... -
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis.
(Journal of cell science, 2019-03-04)Intratumor heterogeneity associates with cancer progression and may account for a substantial portion of therapeutic resistance. Although extensive studies have focused on the origin of the heterogeneity, biological interactions ... -
Effect of Lifestyle Changes after Percutaneous Coronary Intervention on Revascularization.
(BioMed research international, 2020-01)Objective:Whether optimal cardiovascular health metrics may reduce the risk of cardiovascular events in secondary prevention is uncertain. The study was conducted to evaluate the influence of lifestyle changes on clinical ... -
Expanding anti-CD38 immunotherapy for lymphoid malignancies.
(Journal of experimental & clinical cancer research : CR, 2022-06-28)<h4>Background</h4>Lymphoid neoplasms, including multiple myeloma (MM), non-Hodgkin lymphoma (NHL), and NK/T cell neoplasms, are a major cause of blood cancer morbidity and mortality. CD38 (cyclic ADP ribose hydrolase) is ... -
Genetic variant of IRAK2 in the toll-like receptor signaling pathway and survival of non-small cell lung cancer.
(International journal of cancer, 2018-11)The toll-like receptor (TLR) signaling pathway plays an important role in the innate immune responses and antigen-specific acquired immunity. Aberrant activation of the TLR pathway has a significant impact on carcinogenesis ... -
Genetic variants of genes in the Notch signaling pathway predict overall survival of non-small cell lung cancer patients in the PLCO study.
(Oncotarget, 2016-09)The Notch signaling pathway has been shown to have biological significance and therapeutic application in non-small cell lung cancer (NSCLC). We hypothesize that genetic variants of genes in the Notch signaling pathway are ... -
Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression
(Nature Communications, 2020-12)<jats:title>Abstract</jats:title> <jats:p>Tumor necrosis commonly exists and predicts poor prognoses in many cancers. Although it is thought to result from chronic ischemia, the underlying nature and mechanisms ... -
Plant species' origin predicts dominance and response to nutrient enrichment and herbivores in global grasslands.
(Nat Commun, 2015-07-15)Exotic species dominate many communities; however the functional significance of species' biogeographic origin remains highly contentious. This debate is fuelled in part by the lack of globally replicated, systematic data ...
