Browsing by Author "Li, Zhiguo"

Morphologic leukemia-free state in acute myeloid leukemia is sufficient for successful allogeneic hematopoietic stem cell transplant.

Pabon, Cindy M; Li, Zhiguo; Hennig, Therese; de Castro, Carlos; Neff, Jadee L; Horwitz, Mitchell E; LeBlanc, Thomas W; ... (16 authors) (Blood cancer journal, 2021-05-16)

Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery.

Green, Michael MB; Chao, Nelson; Chhabra, Saurabh; Corbet, Kelly; Gasparetto, Cristina; Horwitz, Ari; Li, Zhiguo; ... (18 authors) (J Hematol Oncol, 2018-03-04)

BACKGROUND: The binding of CXCR4 with its ligand (stromal-derived factor-1) maintains hematopoietic stem/progenitor cells (HSPCs) in a quiescent state. We hypothesized that blocking CXCR4/SDF-1 interaction after hematopoietic ...

Rad18 confers hematopoietic progenitor cell DNA damage tolerance independently of the Fanconi Anemia pathway in vivo.

Yang, Yang; Poe, Jonathan C; Yang, Lisong; Fedoriw, Andrew; Desai, Siddhi; Magnuson, Terry; Li, Zhiguo; ... (13 authors) (Nucleic Acids Res, 2016-05-19)

In cultured cancer cells the E3 ubiquitin ligase Rad18 activates Trans-Lesion Synthesis (TLS) and the Fanconi Anemia (FA) pathway. However, physiological roles of Rad18 in DNA damage tolerance and carcinogenesis are unknown ...

Sample size calculation for studies with grouped survival data.

Li, Zhiguo; Wang, Xiaofei; Wu, Yuan; Owzar, Kouros (Statistics in medicine, 2018-06-10)

Grouped survival data arise often in studies where the disease status is assessed at regular visits to clinic. The time to the event of interest can only be determined to be between two adjacent visits or is right censored ...