ALERT: This system is being upgraded on Tuesday December 12. It will not be available for use for several hours that day while the upgrade is in progress. Deposits to DukeSpace will be disabled on Monday December 11, so no new items are to be added to the repository while the upgrade is in progress. Everything should be back to normal by the end of day, December 12.

Now showing items 1-3 of 3

    • Cell-cycle control of cell polarity in yeast. 

      Moran, Kyle D; Kang, Hui; Araujo, Ana V; Zyla, Trevin R; Saito, Koji; Tsygankov, Denis; Lew, Daniel J (The Journal of cell biology, 2019-01)
      In many cells, morphogenetic events are coordinated with the cell cycle by cyclin-dependent kinases (CDKs). For example, many mammalian cells display extended morphologies during interphase but round up into more spherical ...
    • How cells determine the number of polarity sites. 

      Chiou, Jian-Geng; Moran, Kyle D; Lew, Daniel J (eLife, 2021-04-26)
      The diversity of cell morphologies arises, in part, through regulation of cell polarity by Rho-family GTPases. A poorly understood but fundamental question concerns the regulatory mechanisms by which different cells generate ...
    • How Diffusion Impacts Cortical Protein Distribution in Yeasts. 

      Moran, Kyle D; Lew, Daniel J (Cells, 2020-04-30)
      Proteins associated with the yeast plasma membrane often accumulate asymmetrically within the plane of the membrane. Asymmetric accumulation is thought to underlie diverse processes, including polarized growth, stress sensing, ...