Browsing by Author "Moylan, Cynthia A"
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Correction to: Identifying Nonalcoholic Fatty Liver Disease Advanced Fibrosis in the Veterans Health Administration.
Patel, Yuval A; Gifford, Elizabeth J; Glass, Lisa M; Turner, Marsha J; Han, Byungjoo; Moylan, Cynthia A; Choi, Steve; ... (10 authors) (Digestive diseases and sciences, 2018-07-24)The original version of the article unfortunately contained errors in Table 3, Risk Factor column headings "Age > 50 (n = 115)," "Age > 50-64 (n = 154)," and "Age > 65 + (n = 60)." -
Glycemic Control Predicts Severity of Hepatocyte Ballooning and Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease.
Alexopoulos, Anastasia-Stefania; Crowley, Matthew J; Wang, Ying; Moylan, Cynthia A; Guy, Cynthia D; Henao, Ricardo; Piercy, Dawn L; ... (13 authors) (Hepatology (Baltimore, Md.), 2021-03-16)<h4>Background and aims</h4>Whether glycemic control, as opposed to diabetes status, is associated with the severity of nonalcoholic fatty liver disease (NAFLD) is unknown. We aimed to evaluate whether degree of glycemic ... -
Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression.
Du, Kuo; Chitneni, Satish K; Suzuki, Ayako; Wang, Ying; Henao, Ricardo; Hyun, Jeongeun; Premont, Richard T; ... (12 authors) (Cellular and molecular gastroenterology and hepatology, 2020-01)<h4>Background & aims</h4>Nonalcoholic steatohepatitis (NASH) occurs in the context of aberrant metabolism. Glutaminolysis is required for metabolic reprograming of hepatic stellate cells (HSCs) and liver fibrogenesis in ... -
MRI Quantification of Placebo Effect in Nonalcoholic Steatohepatitis Clinical Trials.
Nedrud, Marybeth A; Chaudhry, Mohammad; Middleton, Michael S; Moylan, Cynthia A; Lerebours, Reginald; Luo, Sheng; Farjat, Alfredo; ... (12 authors) (Radiology, 2022-11)Background Several early-phase clinical trials for the treatment of nonalcoholic steatohepatitis (NASH) use liver fat content as measured with the MRI-derived proton density fat fraction (PDFF) for a primary outcome. These ... -
Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches.
Michelotti, Gregory A; Tucker, Anikia; Swiderska-Syn, Marzena; Machado, Mariana Verdelho; Choi, Steve S; Kruger, Leandi; Soderblom, Erik; ... (16 authors) (Gut, 2016-04)OBJECTIVE: The ductular reaction (DR) involves mobilisation of reactive-appearing duct-like cells (RDC) along canals of Hering, and myofibroblastic (MF) differentiation of hepatic stellate cells (HSC) in the space of Disse. ... -
Role of patient factors, preferences, and distrust in health care and access to liver transplantation and organ donation.
Wilder, Julius M; Oloruntoba, Omobonike O; Muir, Andrew J; Moylan, Cynthia A (Liver Transpl, 2016-07)Despite major improvements in access to liver transplantation (LT), disparities remain. Little is known about how distrust in medical care, patient preferences, and the origins shaping those preferences contribute to differences ...