Browsing by Author "Ohnuma, Tetsu"
Now showing items 1-15 of 15
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A nationwide survey of intravenous antimicrobial use in intensive care units in Japan.
Ohnuma, Tetsu; Hayashi, Yoshiro; Yamashita, Kazuto; Marquess, John; Lefor, Alan Kawarai; Sanui, Masamitsu; Japanese Survey of AntimiCRobial Use in ICU PatienTs (JSCRIPT) investigators (International journal of antimicrobial agents, 2018-04)Although most patients in the intensive care unit (ICU) receive antibiotics, little is known about patterns of antibiotic use in ICUs in Japan. The objective of this study was to evaluate the pattern of antibiotic use in ... -
Association of Brain Injury Biomarkers and Circulatory Shock Following Moderate-Severe Traumatic Brain Injury: A TRACK-TBI Study.
Toro, Camilo; Jain, Sonia; Sun, Shelly; Temkin, Nancy; Barber, Jason; Manley, Geoffrey; Komisarow, Jordan M; ... (18 authors) (Journal of neurosurgical anesthesiology, 2021-12)<h4>Introduction</h4>Early circulatory shock following traumatic brain injury (TBI) is a multifactorial process; however, the impact of brain injury biomarkers on the risk of shock has not been evaluated. We examined the ... -
Association of Early Beta-Blocker Exposure and Functional Outcomes in Critically Ill Patients With Moderate to Severe Traumatic Brain Injury: A Transforming Clinical Research and Knowledge in Traumatic Brain Injury Study.
Kelly-Hedrick, Margot; Liu, Sunny Yang; Temkin, Nancy; Barber, Jason; Komisarow, Jordan; Manley, Geoffrey; Ohnuma, Tetsu; ... (20 authors) (Critical care explorations, 2023-09)<h4>Objectives</h4>We aimed to 1) describe patterns of beta-blocker utilization among critically ill patients following moderate-severe traumatic brain injury (TBI) and 2) examine the association of early beta-blocker exposure ... -
Association of Severe Acute Kidney Injury with Mortality and Healthcare Utilization Following Isolated Traumatic Brain Injury.
Luu, David; Komisarow, Jordan; Mills, Brianna M; Vavilala, Monica S; Laskowitz, Daniel T; Mathew, Joseph; James, Michael L; ... (15 authors) (Neurocritical care, 2021-01-13)<h4>Background/objective</h4>Traumatic brain injury (TBI) is a leading cause of morbidity, mortality, and disability in the USA. While cardiopulmonary dysfunction can result in poor outcomes following severe TBI, the impact ... -
Change to Mixed-Lipid Emulsion From Soybean Oil-Based Lipid Emulsion in Pediatric Patients.
Haines, Krista L; Ohnuma, Tetsu; Hornik, Chi Dang; Grisel, Braylee; Leraas, Harold; Trujillo, Charles N; Krishnamoorthy, Vijay; ... (9 authors) (JAMA network open, 2023-09)<h4>Importance</h4>Critically ill pediatric patients often require parenteral nutrition (PN) in the intensive care unit (ICU). Literature suggests mixed lipid emulsions (LE) with soybean oil reduction strategies may improve ... -
Changes in analgesic strategies for lobectomy from 2009 to 2018
Lo, Theresa; Schiller, Robin; Raghunathan, Karthik; Krishnamoorthy, Vijay; Jawitz, Oliver K; Pyati, Srinivas; Van De Ven, Thomas; ... (10 authors) (JTCVS Open, 2021-06-01)Objective: To evaluate trends in the use of epidural analgesia and nonopioid and opioid analgesics for patients undergoing lobectomy from 2009 to 2018. Methods: We queried the Premier database for adult patients undergoing ... -
Effects of Acetaminophen, NSAIDs, Gabapentinoids, and Their Combinations on Postoperative Pulmonary Complications After Total Hip or Knee Arthroplasty.
Ohnuma, Tetsu; Raghunathan, Karthik; Ellis, Alan R; Whittle, John; Pyati, Srinivas; Bryan, William E; Pepin, Marc J; ... (9 authors) (Pain medicine (Malden, Mass.), 2020-02-26)OBJECTIVE:Multimodal analgesia has gained popularity in total hip arthroplasty (THA) and total knee arthroplasty (TKA), but large multicenter studies evaluating specific analgesic combinations are lacking. DESIGN:A retrospective ... -
Hospital change to mixed lipid emulsion from soybean oil-based lipid emulsion for parenteral nutrition in hospitalized and critically ill adults improves outcomes: a pre–post-comparative study
Haines, Krista L; Ohnuma, Tetsu; Trujillo, Charles; Osamudiamen, Obanor; Krishnamoorthy, Vijay; Raghunathan, Karthik; Wischmeyer, Paul E<jats:title>Abstract</jats:title><jats:sec> <jats:title>Introduction</jats:title> <jats:p>Early data suggest use of a mixed lipid emulsion (LE) with a soybean oil reduction strategy in parenteral ... -
Hospital mortality of patients aged 80 and older after surgical repair for type A acute aortic dissection in Japan.
Ohnuma, Tetsu; Shinjo, Daisuke; Fushimi, Kiyohide (Medicine, 2016-08)To evaluate whether patients aged 80 and older have higher risk of hospital mortality after repair of type A acute aortic dissection (TAAAD).Emergency surgery for TAAAD in patients aged 80 and older remains a controversial ... -
Impact of early postoperative oral nutritional supplement utilization on clinical outcomes in colorectal surgery.
Williams, David GA; Ohnuma, Tetsu; Krishnamoorthy, Vijay; Raghunathan, Karthik; Sulo, Suela; Cassady, Bridget A; Hegazi, Refaat; ... (8 authors) (Perioperative medicine (London, England), 2020-01)Background:Small randomized trials of early postoperative oral nutritional supplementation (ONS) suggest various health benefits following colorectal surgery (CRS). However, real-world evidence of the impact of early ONS ... -
Mechanical thrombectomy for perioperative ischemic stroke following elective inpatient surgery in the United States.
Shah, Shreyansh; Hatfield, Jordan; Fuller, Matthew; Ohnuma, Tetsu; Luke James, Michael; Bartz, Raquel R; Raghunathan, Karthik; ... (9 authors) (Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2022-05-13)Perioperative ischemic stroke significantly increases morbidity and mortality in patients undergoing elective surgery. Mechanical thrombectomy can improve ischemic stroke outcomes, but frequency and trend of its utilization ... -
Observational Research Using Propensity Scores.
Raghunathan, Karthik; Layton, J Bradley; Ohnuma, Tetsu; Shaw, Andrew D (Adv Chronic Kidney Dis, 2016-11)In most observational studies, treatments or other "exposures" (in an epidemiologic sense) do not occur at random. Instead, treatments or other such interventions depend on several patient-related and patient-independent ... -
Racial and Ethnic Differences in the Prevalence of Do-Not-Resuscitate Orders among Older Adults with Severe Traumatic Brain Injury.
Hatfield, Jordan; Fah, Megan; Girden, Alex; Mills, Brianna; Ohnuma, Tetsu; Haines, Krista; Cobert, Julien; ... (15 authors) (Journal of intensive care medicine, 2022-05-22)<h4>Background</h4>Older adults suffering from traumatic brain injury (TBI) are subject to higher injury burden and mortality. Do Not Resuscitate (DNR) orders are used to provide care aligned with patient wishes, but they ... -
Utilization of Brain Tissue Oxygenation Monitoring and Association with Mortality Following Severe Traumatic Brain Injury.
Komisarow, Jordan M; Toro, Camilo; Curley, Jonathan; Mills, Brianna; Cho, Christopher; Simo, Georges Motchoffo; Vavilala, Monica S; ... (14 authors) (Neurocritical care, 2022-04)<h4>Background</h4>The aim of this study was to describe the utilization patterns of brain tissue oxygen (PbtO2) monitoring following severe traumatic brain injury (TBI) and determine associations with mortality, health ... -
Validity of low-intensity continuous renal replacement therapy*.
Uchino, Shigehiko; Toki, Noriyoshi; Takeda, Kenta; Ohnuma, Tetsu; Namba, Yoshitomo; Katayama, Shinshu; Kawarazaki, Hiroo; ... (13 authors) (Critical care medicine, 2013-11)OBJECTIVE: To study the hospital mortality of patients with severe acute kidney injury treated with low-intensity continuous renal replacement therapy. DESIGN: Multicenter retrospective observational study (Japanese Society ...