Browsing by Author "Orlando, Lori A"
Now showing items 1-17 of 17
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Challenges and strategies for implementing genomic services in diverse settings: experiences from the Implementing GeNomics In pracTicE (IGNITE) network.
(BMC Med Genomics, 2017-05-22)BACKGROUND: To realize potential public health benefits from genetic and genomic innovations, understanding how best to implement the innovations into clinical care is important. The objective of this study was to synthesize ... -
Clinical implementation of an oncology-specific family health history risk assessment tool.
(Hereditary cancer in clinical practice, 2021-03-20)<h4>Background</h4>The presence of hereditary cancer syndromes in cancer patients can have an impact on current clinical care and post-treatment prevention and surveillance measures. Several barriers inhibit identification ... -
Clinical utility of a Web-enabled risk-assessment and clinical decision support program.
(Genet Med, 2016-10)PURPOSE: Risk-stratified guidelines can improve quality of care and cost-effectiveness, but their uptake in primary care has been limited. MeTree, a Web-based, patient-facing risk-assessment and clinical decision support ... -
Cost-effectiveness analysis of the diagnosis of meniscus tears.
(Am J Sports Med, 2015-01)BACKGROUND: Diagnostic imaging represents the fastest growing segment of costs in the US health system. This study investigated the cost-effectiveness of alternative diagnostic approaches to meniscus tears of the knee, a ... -
Economic evaluation of access to musculoskeletal care: the case of waiting for total knee arthroplasty.
(BMC Musculoskelet Disord, 2014-01-18)BACKGROUND: The projected demand for total knee arthroplasty is staggering. At its root, the solution involves increasing supply or decreasing demand. Other developed nations have used rationing and wait times to distribute ... -
Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network.
(Genetics in medicine : official journal of the American College of Medical Genetics, 2021-03-29)<h4>Purpose</h4>A critical gap in the adoption of genomic medicine into medical practice is the need for the rigorous evaluation of the utility of genomic medicine interventions.<h4>Methods</h4>The Implementing Genomics ... -
Experience and Perceptions of a Family Health History Risk Assessment Tool among Multi-Ethnic Asian Breast Cancer Patients.
(J Pers Med, 2021-10-19)A family health history-based risk assessment is particularly valuable for guiding cancer screening and treatment strategies, yet an optimal implementation depends upon end-users' values and needs. This is not only true ... -
Impact of Genetic Testing and Family Health History Based Risk Counseling on Behavior Change and Cognitive Precursors for Type 2 Diabetes.
(J Genet Couns, 2017-02)Family health history (FHH) in the context of risk assessment has been shown to positively impact risk perception and behavior change. The added value of genetic risk testing is less certain. The aim of this study was to ... -
Making genomic medicine evidence-based and patient-centered: a structured review and landscape analysis of comparative effectiveness research.
(Genet Med, 2017-04-13)Comparative effectiveness research (CER) in genomic medicine (GM) measures the clinical utility of using genomic information to guide clinical care in comparison to appropriate alternatives. We summarized findings of high-quality ... -
Patient beliefs and behaviors about genomic risk for type 2 diabetes: Implications for prevention
(Journal of Health Communication, 2015-01-01)Copyright © Taylor & Francis Group, LLC 2015.Type 2 diabetes is a major health burden in the United States, and population trends suggest this burden will increase. High interest in, and increased availability of, testing ... -
Protocol for implementation of family health history collection and decision support into primary care using a computerized family health history system.
(BMC Health Serv Res, 2011-10-11)BACKGROUND: The CDC's Family History Public Health Initiative encourages adoption and increase awareness of family health history. To meet these goals and develop a personalized medicine implementation science research agenda, ... -
Protocol for the "Implementation, adoption, and utility of family history in diverse care settings" study.
(Implement Sci, 2015-11-24)BACKGROUND: Risk assessment with a thorough family health history is recommended by numerous organizations and is now a required component of the annual physical for Medicare beneficiaries under the Affordable Care Act. ... -
Surgeon Applications of Patient Preferences in Treatment Decision Making for First-Time Anterior Shoulder Dislocation.
(Orthopaedic journal of sports medicine, 2020-12-04)<h4>Background</h4>Treatment of a first-time anterior shoulder dislocation (FTASD) is sensitive to patient preferences. The operative or nonoperative management debate provides an excellent opportunity to learn how surgeons ... -
The chronic kidney disease model: a general purpose model of disease progression and treatment.
(BMC medical informatics and decision making, 2011-06-16)<h4>Background</h4>Chronic kidney disease (CKD) is the focus of recent national policy efforts; however, decision makers must account for multiple therapeutic options, comorbidities and complications. The objective of the ... -
The enduring importance of family health history in the era of genomic medicine and risk assessment.
(Per Med, 2020-04-22)Improving disease risk prediction and tailoring preventive interventions to patient risk factors is one of the primary goals of precision medicine. Family health history is the traditional approach to quickly gather genetic ... -
The IGNITE network: a model for genomic medicine implementation and research.
(BMC Med Genomics, 2016-01-05)BACKGROUND: Patients, clinicians, researchers and payers are seeking to understand the value of using genomic information (as reflected by genotyping, sequencing, family history or other data) to inform clinical decision-making. ... -
Understanding Preferences for Treatment After Hypothetical First-Time Anterior Shoulder Dislocation: Surveying an Online Panel Utilizing a Novel Shared Decision-Making Tool.
(Orthop J Sports Med, 2017-03)BACKGROUND: Although surgical management of a first-time anterior shoulder dislocation (FTASD) can reduce the risk of recurrent dislocation, other treatment characteristics, costs, and outcomes are important to patients ...
