Browsing by Author "Patkar, Ashwin A"
Now showing items 1-18 of 18
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Addressing the Side Effects of Contemporary Antidepressant Drugs: A Comprehensive Review.
(Chonnam medical journal, 2018-05-25)Randomized trials have shown that selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) have better safety profiles than classical tricyclic antidepressants (TCAs). However, ... -
An integrated alcohol abuse and medical treatment model for patients with hepatitis C.
(Dig Dis Sci, 2012-04)BACKGROUND: Patients with chronic hepatitis C virus (HCV) infection have high rates of alcohol consumption, which is associated with progression of fibrosis and lower response rates to HCV treatment. AIMS: This prospective ... -
An item response theory modeling of alcohol and marijuana dependences: a National Drug Abuse Treatment Clinical Trials Network study.
(Journal of studies on alcohol and drugs, 2009-05)OBJECTIVE:The aim of this study was to examine psychometric properties of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), diagnostics criteria for alcohol and marijuana dependences among ... -
Early outcomes following low dose naltrexone enhancement of opioid detoxification.
(The American journal on addictions, 2009-03)Although withdrawal severity and treatment completion are the initial focus of opioid detoxification, post-detoxification outcome better defines effective interventions. Very low dose naltrexone (VLNTX) in addition to methadone ... -
Effectiveness of low-dose naltrexone in the post-detoxification treatment of opioid dependence.
(Journal of clinical psychopharmacology, 2007-10)BACKGROUND: The clinical use of naltrexone (NTX) in the treatment of opioid dependence has been limited because of poor compliance and inconsistent outcomes. In particular, the therapeutic benefit of extended treatment with ... -
Guidance for switching from off-label antipsychotics to pimavanserin for Parkinson's disease psychosis: an expert consensus.
(CNS spectrums, 2018-12)Patients with Parkinson's disease psychosis (PDP) are often treated with an atypical antipsychotic, especially quetiapine or clozapine, but side effects, lack of sufficient efficacy, or both may motivate a switch to pimavanserin, ... -
Hallucinogen use disorders among adult users of MDMA and other hallucinogens.
(The American journal on addictions, 2008-09)We investigated the prevalence, patterns, and correlates of past-year DSM-IV hallucinogen use disorders (HUDs) among past-year users of MDMA and other hallucinogens from a sample of Americans 18 or older (n = 37,227). Users ... -
Heterogeneity of stimulant dependence: a national drug abuse treatment clinical trials network study.
(The American journal on addictions, 2009-05)We investigated the presence of DSM-IV subtyping for dependence on cocaine and amphetamines (with versus without physical dependence) among outpatient stimulant users enrolled in a multisite study of the Clinical Trials ... -
Infrequent illicit methadone use among stimulant-using patients in methadone maintenance treatment programs: a national drug abuse treatment clinical trials network study.
(The American journal on addictions, 2008-07)We sought to determine the prevalence, patterns, and correlates of past-month illicit methadone use and history of regular illicit use among stimulant-using methadone maintenance treatment patients. We obtained self-reported ... -
Non-invasive brain stimulation modalities for the treatment and prevention of opioid use disorder: a systematic review of the literature
(Journal of Addictive Diseases, 2020-01-01)© 2020, © 2020 Taylor & Francis Group, LLC. The U.S. is currently facing an unprecedented epidemic of opioid-related deaths. Despite the efficacy of the current treatments for opioid use disorder (OUD), including psychosocial ... -
Non-prescribed use of pain relievers among adolescents in the United States.
(Drug and alcohol dependence, 2008-04)We examined gender-specific prevalences, patterns, and correlates of non-prescribed use of pain relievers - mainly opioids - in a representative sample of American adolescents (N=18,678).Data were drawn from the public use ... -
Prescription pain reliever abuse and dependence among adolescents: a nationally representative study.
(Journal of the American Academy of Child and Adolescent Psychiatry, 2008-09)We examined the prevalence, patterns, and correlates of adolescents' abuse, subthreshold dependence ("diagnostic orphans"), and dependence on prescription pain relievers (PPRs) such as opioids in a representative national ... -
Problem drinking and low-dose naltrexone-assisted opioid detoxification.
(Journal of studies on alcohol and drugs, 2011-05)OBJECTIVE:The influence of alcohol use on opioid dependence is a major problem that warrants a search for more effective treatment strategies. The addition of very-low-dose naltrexone (VLNTX) to methadone taper was recently ... -
Reduced cannabis use after low-dose naltrexone addition to opioid detoxification.
(Journal of clinical psychopharmacology, 2010-08) -
The combination very low-dose naltrexone-clonidine in the management of opioid withdrawal.
(The American journal of drug and alcohol abuse, 2012-05)The management of withdrawal absorbs substantial clinical efforts in opioid dependence (OD). The real challenge lies in improving current pharmacotherapies. Although widely used, clonidine causes problematic adverse effects ... -
The construct and measurement equivalence of cocaine and opioid dependences: a National Drug Abuse Treatment Clinical Trials Network (CTN) study.
(Drug and alcohol dependence, 2009-08)INTRODUCTION:Although DSM-IV criteria are widely used in making diagnoses of substance use disorders, gaps exist regarding diagnosis classification, use of dependence criteria, and effects of measurement bias on diagnosis ... -
The high prevalence of substance use disorders among recent MDMA users compared with other drug users: Implications for intervention.
(Addictive behaviors, 2009-08)In light of the resurgence in MDMA use and its association with polysubstance use, we investigated the 12-month prevalence of substance use disorders (SUDs) among adult MDMA users to determine whether they are at risk of ... -
The impact of the CONSORT statement on reporting of randomized clinical trials in psychiatry.
(Contemporary clinical trials, 2009-03)To determine whether the CONSORT recommendations influenced the quality of reporting of randomized controlled trials (RCTs) in the field of psychiatry, we evaluated the quality of clinical trial reports before and after ...
