Browsing by Author "Penn, RB"

Now showing items 1-1 of 1

Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart.

Eckhart, AD; Duncan, SJ; Penn, RB; Benovic, JL; Lefkowitz, RJ; Koch, WJ (Circ Res, 2000-01-07)

G protein-coupled receptor kinases (GRKs) phosphorylate activated G protein-coupled receptors, including alpha(1B)-adrenergic receptors (ARs), resulting in desensitization. In vivo analysis of GRK substrate selectivity has ...