Now showing items 1-7 of 7

    • Comparative genomics reveals insights into avian genome evolution and adaptation. 

      Alfaro-Núñez, A; Alström, P; An, N; Antunes, A; Avian Genome Consortium; Bertelsen, MF; Borges, R; ... (106 authors) (Science, 2014-12-12)
      Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian species representing all major extant clades. ...
    • Convergent transcriptional specializations in the brains of humans and song-learning birds. 

      Pfenning, Andreas R; Hara, Erina; Whitney, Osceola; Rivas, Miriam V; Wang, Rui; Roulhac, Petra L; Howard, Jason T; ... (25 authors) (Science, 2014-12-12)
      Song-learning birds and humans share independently evolved similarities in brain pathways for vocal learning that are essential for song and speech and are not found in most other species. Comparisons of brain transcriptomes ...
    • Core and region-enriched networks of behaviorally regulated genes and the singing genome. 

      Whitney, Osceola; Pfenning, Andreas R; Howard, Jason T; Blatti, Charles A; Liu, Fang; Ward, James M; Wang, Rui; ... (14 authors) (Science, 2014-12-12)
      Songbirds represent an important model organism for elucidating molecular mechanisms that link genes with complex behaviors, in part because they have discrete vocal learning circuits that have parallels with those that ...
    • Genome-wide identification of calcium-response factor (CaRF) binding sites predicts a role in regulation of neuronal signaling pathways 

      Pfenning, Andreas R; Kim, Tae-Kyung; Spotts, James M; Hemberg, Martin; Su, Dan; West, Anne E (PLoS ONE, 2010)
      Calcium-Response Factor (CaRF) was first identified as a transcription factor based on its affinity for a neuronal-selective calcium-response element (CaRE1) in the gene encoding Brain-Derived Neurotrophic Factor (BDNF). ...
    • Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns. 

      Chen, CC; Feenders, G; Hara, E; Horita, H; Howard, J; Jarvis, Erich David; Jarvis, Erich David; ... (19 authors) (J Comp Neurol, 2013-11)
      Based on quantitative cluster analyses of 52 constitutively expressed or behaviorally regulated genes in 23 brain regions, we present a global view of telencephalic organization of birds. The patterns of constitutively expressed ...
    • Molecular profiling of the developing avian telencephalon: regional timing and brain subdivision continuities. 

      Chen, Chun-Chun; Winkler, Candace M; Pfenning, Andreas R; Jarvis, Erich D (J Comp Neurol, 2013-11)
      In our companion study (Jarvis et al. [2013] J Comp Neurol. doi: 10.1002/cne.23404) we used quantitative brain molecular profiling to discover that distinct subdivisions in the avian pallium above and below the ventricle ...
    • The genome of a songbird. 

      Warren, Wesley C; Clayton, David F; Ellegren, Hans; Arnold, Arthur P; Hillier, Ladeana W; Künstner, Axel; Searle, Steve; ... (82 authors) (Nature, 2010-04-01)
      The zebra finch is an important model organism in several fields with unique relevance to human neuroscience. Like other songbirds, the zebra finch communicates through learned vocalizations, an ability otherwise documented ...