Browsing by Author "Ramanujam, Nirmala"
Now showing items 1-4 of 4
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Instrument independent diffuse reflectance spectroscopy.
Yu, Bing; Fu, Henry L; Ramanujam, Nirmala (J Biomed Opt, 2011-01)Diffuse reflectance spectroscopy with a fiber optic probe is a powerful tool for quantitative tissue characterization and disease diagnosis. Significant systematic errors can arise in the measured reflectance spectra and ... -
Noninvasive monitoring of tissue hemoglobin using UV-VIS diffuse reflectance spectroscopy: a pilot study.
Bender, Janelle E; Shang, Allan B; Moretti, Eugene W; Yu, Bing; Richards, Lisa M; Ramanujam, Nirmala (Opt Express, 2009-12-21)We conducted a pilot study on 10 patients undergoing general surgery to test the feasibility of diffuse reflectance spectroscopy in the visible wavelength range as a noninvasive monitoring tool for blood loss during surgery. ... -
Rapid ratiometric determination of hemoglobin concentration using UV-VIS diffuse reflectance at isosbestic wavelengths.
Phelps, Janelle E; Vishwanath, Karthik; Chang, Vivide TC; Ramanujam, Nirmala (Opt Express, 2010-08-30)We developed a ratiometric method capable of estimating total hemoglobin concentration from optically measured diffuse reflectance spectra. The three isosbestic wavelength ratio pairs that best correlated to total hemoglobin ... -
Towards a field-compatible optical spectroscopic device for cervical cancer screening in resource-limited settings: effects of calibration and pressure.
Chang, Vivide Tuan-Chyan; Merisier, Delson; Yu, Bing; Walmer, David K; Ramanujam, Nirmala (Opt Express, 2011-09-12)Quantitative optical spectroscopy has the potential to provide an effective low cost, and portable solution for cervical pre-cancer screening in resource-limited communities. However, clinical studies to validate the use ...