Browsing by Author "Riaz, Haris"
Now showing items 1-10 of 10
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A Bayesian network meta-analysis of PCSK9 inhibitors, statins and ezetimibe with or without statins for cardiovascular outcomes
(European Journal of Preventive Cardiology, 2018-05-01)© 2018, © The European Society of Cardiology 2018. Background: The comparative effects of statins, ezetimibe with or without statins and proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors remain unassessed. ... -
Association Between Obesity and Cardiovascular Outcomes: A Systematic Review and Meta-analysis of Mendelian Randomization Studies.
(JAMA network open, 2018-11-02)Importance:Although dyslipidemia has been consistently shown to be associated with atherogenesis, an association between obesity and cardiovascular disease outcomes remains controversial. Mendelian randomization can minimize ... -
Best Practice Advisories Should Not Replace Good Clinical Acumen.
(Am J Med, 2016-09-15) -
Conflicts of Interest and Outcomes of Cardiovascular Trials.
(Am J Cardiol, 2016-03-01)Conflicts of interests have long been recognized as potential sources of influence in the conduct and reporting of clinical trials. This controversy was again rekindled after the publication of the latest statin guidelines ... -
Evaluation of Industrial Compensation to Cardiologists in 2015.
(Am J Cardiol, 2017-12-15)The categorization and characterization of pharmaceutical and device manufacturers or group purchasing organization payments to clinicians is an important step toward assessing conflicts of interest and the potential impact ... -
Impact of Funding Source on Clinical Trial Results Including Cardiovascular Outcome Trials.
(Am J Cardiol, 2015-12-15)Previous authors have suggested a higher likelihood for industry-sponsored (IS) studies to have positive outcomes than non-IS studies, though the influence of publication bias was believed to be a likely confounder. We attempted ... -
Meta-analysis of Placebo-Controlled Randomized Controlled Trials on the Prevalence of Statin Intolerance.
(Am J Cardiol, 2017-09-01)The prevalence of intolerance varies widely. Stopping statin therapy is associated with worse outcomes in patients with cardiovascular disease. Despite extensive studies, the benefits and risks of statins continue to be ... -
Safety and Use of Anticoagulation After Aortic Valve Replacement With Bioprostheses: A Meta-Analysis.
(Circ Cardiovasc Qual Outcomes, 2016-05)BACKGROUND: The American College of Cardiology guidelines recommend 3 months of anticoagulation after replacement of the aortic valve with a bioprosthesis. However, there remains great variability in the current clinical ... -
Should Physicians be Encouraged to use Generic Names and to Prescribe Generic Drugs?
(Am J Cardiol, 2016-06-01)While using the brand names seems like a trivial issue at the outset, using these names is inherently problematic. Cardiovascular drugs remain the most commonly prescribed drugs by the physicians. The junior doctors are ... -
Transcatheter closure of patent foramen ovale following cryptogenic stroke: An updated meta-analysis of randomized controlled trials.
(American heart journal, 2018-05)Transcatheter closure of patent foramen ovale (PFO) after cryptogenic stroke has long been a contentious issue. Herein, we pool aggregate data examining safety and efficacy of transcatheter closure of PFO compared with medical ...
