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    • Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice. 

      Gardenghi, Sara; Ramos, Pedro; Marongiu, Maria Franca; Melchiori, Luca; Breda, Laura; Guy, Ella; Muirhead, Kristen; ... (19 authors) (J Clin Invest, 2010-12)
      Excessive iron absorption is one of the main features of β-thalassemia and can lead to severe morbidity and mortality. Serial analyses of β-thalassemic mice indicate that while hemoglobin levels decrease over time, ...