Browsing by Author "Schwinn, DA"
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Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor.
Cotecchia, S; Schwinn, DA; Randall, RR; Lefkowitz, RJ; Caron, MG; Kobilka, BK (Proc Natl Acad Sci U S A, 1988-10)The cDNA for the Syrian hamster alpha 1-adrenergic receptor has been cloned with oligonucleotides corresponding to the partial amino acid sequence of the receptor protein purified from DDT1MF-2 smooth muscle cells. The deduced ... -
Structural basis for receptor subtype-specific regulation revealed by a chimeric beta 3/beta 2-adrenergic receptor.
Liggett, SB; Freedman, NJ; Schwinn, DA; Lefkowitz, RJ (Proc Natl Acad Sci U S A, 1993-04-15)The physiological significance of multiple G-protein-coupled receptor subtypes, such as the beta-adrenergic receptors (beta ARs), remains obscure, since in many cases several subtypes activate the same effector and utilize ...