Browsing by Author "Shankar-Hari, Manu"
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Sepsis Subclasses: A Framework for Development and Interpretation.
DeMerle, Kimberley M; Angus, Derek C; Baillie, J Kenneth; Brant, Emily; Calfee, Carolyn S; Carcillo, Joseph; Chang, Chung-Chou H; ... (30 authors) (Critical care medicine, 2021-05)Sepsis is defined as a dysregulated host response to infection that leads to life-threatening acute organ dysfunction. It afflicts approximately 50 million people worldwide annually and is often deadly, even when evidence-based ... -
Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.
ATTACC Investigators; ACTIV-4a Investigators; REMAP-CAP Investigators; Lawler, Patrick R; Goligher, Ewan C; Berger, Jeffrey S; Neal, Matthew D; ... (181 authors) (The New England journal of medicine, 2021-08-04)<h4>Background</h4>Thrombosis and inflammation may contribute to the risk of death and complications among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation may improve ...