Browsing by Author "Shapiro, Nathan I"

A Randomized Trial of Protocol-Based Care for Early Septic Shock

ProCESS Investigators; Yealy, Donald M; Kellum, John A; Huang, David T; Barnato, Amber E; Weissfeld, Lisa A; Pike, Francis; ... (14 authors) (New England Journal of Medicine, 2014-05)

Perioperative Quality Initiative (POQI) consensus statement on fundamental concepts in perioperative fluid management: fluid responsiveness and venous capacitance

Martin, Greg S; Kaufman, David A; Marik, Paul E; Shapiro, Nathan I; Levett, Denny ZH; Whittle, John; MacLeod, David B; ... (21 authors) (Perioperative Medicine, 2020-12)

Sepsis Subclasses: A Framework for Development and Interpretation.

DeMerle, Kimberley M; Angus, Derek C; Baillie, J Kenneth; Brant, Emily; Calfee, Carolyn S; Carcillo, Joseph; Chang, Chung-Chou H; ... (30 authors) (Critical care medicine, 2021-05)

Sepsis is defined as a dysregulated host response to infection that leads to life-threatening acute organ dysfunction. It afflicts approximately 50 million people worldwide annually and is often deadly, even when evidence-based ...

Systematic Molecular Phenotyping: A Path Toward Precision Emergency Medicine?

Limkakeng, Alexander T; Monte, Andrew A; Kabrhel, Christopher; Puskarich, Michael; Heitsch, Laura; Tsalik, Ephraim L; Shapiro, Nathan I (Acad Emerg Med, 2016-10)

Precision medicine is an emerging approach to disease treatment and prevention that considers variability in patient genes, environment, and lifestyle. However, little has been written about how such research impacts emergency ...