Browsing by Author "Shibata, Yoichiro"
Now showing items 1-3 of 3
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Comparative Serum Challenges Show Divergent Patterns of Gene Expression and Open Chromatin in Human and Chimpanzee.
(Genome biology and evolution, 2018-03)Humans experience higher rates of age-associated diseases than our closest living evolutionary relatives, chimpanzees. Environmental factors can explain many of these increases in disease risk, but species-specific genetic ... -
Genome-wide Cross-species Analysis Linking Open Chromatin, Differential Expression and Positive Selection
(2012)Deciphering the molecular mechanisms driving the phenotypic differences between humans and primates remains a daunting challenge. Mutations found in protein coding DNA alone has not been able to explain these phenotypic ... -
Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection.
(Scientific reports, 2016-09-27)On Earth, biological systems have evolved in response to environmental stressors, interactions dictated by physical forces that include gravity. The absence of gravity is an extreme stressor and the impact of its absence ...
