Browsing by Author "Simuni, Tanya"
Now showing items 1-4 of 4
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Application of Longitudinal Item Response Theory Models to Modeling Parkinson's Disease Progression.
(CPT: pharmacometrics & systems pharmacology, 2022-07-27)The Movement Disorder Society revised version of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Parts 2 and 3 reflect patient-reported functional impact and clinician-reported severity of motor signs of Parkinson's ... -
Dissecting the Domains of Parkinson's Disease: Insights from Longitudinal Item Response Theory Modeling.
(Movement disorders : official journal of the Movement Disorder Society, 2022-09)<h4>Background</h4>Longitudinal item response theory (IRT) models previously suggested that the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) motor examination has two salient domains, tremor ... -
Guidance for switching from off-label antipsychotics to pimavanserin for Parkinson's disease psychosis: an expert consensus.
(CNS spectrums, 2018-12)Patients with Parkinson's disease psychosis (PDP) are often treated with an atypical antipsychotic, especially quetiapine or clozapine, but side effects, lack of sufficient efficacy, or both may motivate a switch to pimavanserin, ... -
Novel Approach to Movement Disorder Society–Unified Parkinson's Disease Rating Scale Monitoring in Clinical Trials: Longitudinal Item Response Theory Models
(Movement Disorders Clinical Practice, 2021-01-01)Background: Although nontremor and tremor Part 3 Movement Disorder Society–Unified Parkinson's Disease Rating Scale items measure different impairment domains, their distinct progression and drug responsivity remain unstudied ...
