Now showing items 1-2 of 2

    • Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis. 

      PRISM Investigators; Rowan, Kathryn M; Angus, Derek C; Bailey, Michael; Barnato, Amber E; Bellomo, Rinaldo; Canter, Ruth R; ... (24 authors) (The New England journal of medicine, 2017-06)
      BACKGROUND:After a single-center trial and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality from septic shock, three multicenter trials (ProCESS, ARISE, and ProMISe) showed no benefit. ...
    • Seven unconfirmed ideas to improve future ICU practice. 

      Marini, John J; De Backer, Daniel; Ince, Can; Singer, Mervyn; Van Haren, Frank; Westphal, Martin; Wischmeyer, Paul (Crit Care, 2017-12-28)
      With imprecise definitions, inexact measurement tools, and flawed study execution, our clinical science often lags behind bedside experience and simply documents what appear to be the apparent faults or validity of ongoing ...