Now showing items 1-3 of 3

    • A functional polymorphism in the 5HTR2C gene associated with stress responses also predicts incident cardiovascular events. 

      Babyak, MA; Becker, RC; Brummett, BH; Chryst-Ladd, M; Craig, Damian; Hauser, Elizabeth Rebecca; Haynes, Carol; ... (13 authors) (PLoS One, 2013)
      Previously we have shown that a functional nonsynonymous single nucleotide polymorphism (rs6318) of the 5HTR2C gene located on the X-chromosome is associated with hypothalamic-pituitary-adrenal axis response to a stress ...
    • Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. 

      Center for HIV/AIDS Vaccine Immunology (CHAVI); Cirulli Rogers, Elizabeth T; Ge, Dongliang; Goedert, JJ; Goldstein, David Benjamin; Heinzen, EL; Maia, JM; ... (10 authors) (Genome Biol, 2010)
      BACKGROUND: There is considerable interest in the development of methods to efficiently identify all coding variants present in large sample sets of humans. There are three approaches possible: whole-genome sequencing, ...
    • The characterization of twenty sequenced human genomes. 

      Campbell, CR; Cirulli Rogers, Elizabeth T; Dickson, SP; Fellay, J; Ge, Dongliang; Goedert, JJ; Goldstein, David Benjamin; ... (25 authors) (PLoS Genet, 2010-09-09)
      We present the analysis of twenty human genomes to evaluate the prospects for identifying rare functional variants that contribute to a phenotype of interest. We sequenced at high coverage ten "case" genomes from individuals ...