Now showing items 1-4 of 4

    • Common genetic variation and the control of HIV-1 in humans. 

      Antonarakis, SE; Beckmann, JS; Carrington, Mary; Castagna, A; Cirulli Rogers, Elizabeth T; Colombo, S; Cozzi-Lepri, A; ... (38 authors) (PLoS Genet, 2009-12)
      To extend the understanding of host genetic determinants of HIV-1 control, we performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects. The study was powered to detect common genetic variants ...
    • Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. 

      Center for HIV/AIDS Vaccine Immunology (CHAVI); Cirulli Rogers, Elizabeth T; Ge, Dongliang; Goedert, JJ; Goldstein, David Benjamin; Heinzen, EL; Maia, JM; ... (10 authors) (Genome Biol, 2010)
      BACKGROUND: There is considerable interest in the development of methods to efficiently identify all coding variants present in large sample sets of humans. There are three approaches possible: whole-genome sequencing, ...
    • The characterization of twenty sequenced human genomes. 

      Campbell, CR; Cirulli Rogers, Elizabeth T; Dickson, SP; Fellay, J; Ge, Dongliang; Goedert, JJ; Goldstein, David Benjamin; ... (25 authors) (PLoS Genet, 2010-09-09)
      We present the analysis of twenty human genomes to evaluate the prospects for identifying rare functional variants that contribute to a phenotype of interest. We sequenced at high coverage ten "case" genomes from individuals ...
    • Whole-Genome Sequencing of a Single Proband Together with Linkage Analysis Identifies a Mendelian Disease Gene 

      Avramopoulos, D; Cirulli Rogers, Elizabeth T; Ge, Dongliang; Goldstein, David Benjamin; Gumbs, Curtis E; Hoover-Fong, JE; Maia, JM; ... (16 authors) (PLoS Genetics, 2010-06-17)