Browsing by Author "Song, Allen W"
Now showing items 1-14 of 14
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Association between increased magnetic susceptibility of deep gray matter nuclei and decreased motor function in healthy adults.
(Neuroimage, 2015-01-15)In the human brain, iron is more prevalent in gray matter than in white matter, and deep gray matter structures, particularly the globus pallidus, putamen, caudate nucleus, substantia nigra, red nucleus, and dentate nucleus, ... -
BOLD signal compartmentalization based on the apparent diffusion coefficient.
(Magn Reson Imaging, 2002-09)Functional MRI (fMRI) can detect blood oxygenation level dependent (BOLD) hemodynamic responses secondary to neuronal activity. The most commonly used method for detecting fMRI signals is the gradient-echo echo-planar imaging ... -
Brain structural connectivity increases concurrent with functional improvement: evidence from diffusion tensor MRI in children with cerebral palsy during therapy.
(NeuroImage. Clinical, 2015-01-09)Cerebral Palsy (CP) refers to a heterogeneous group of permanent but non-progressive movement disorders caused by injury to the developing fetal or infant brain (Bax et al., 2005). Because of its serious long-term consequences, ... -
Correction for Eddy Current-Induced Echo-Shifting Effect in Partial-Fourier Diffusion Tensor Imaging.
(Biomed Res Int, 2015)In most diffusion tensor imaging (DTI) studies, images are acquired with either a partial-Fourier or a parallel partial-Fourier echo-planar imaging (EPI) sequence, in order to shorten the echo time and increase ... -
Cortical iron mediates age-related decline in fluid cognition.
(Human brain mapping, 2022-02)Brain iron dyshomeostasis disrupts various critical cellular functions, and age-related iron accumulation may contribute to deficient neurotransmission and cell death. While recent studies have linked excessive brain iron ... -
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Human Brain Mapping, 2014-06)As indicated by several recent studies, magnetic susceptibility of the brain is influenced mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination and iron deposition in the brain evolve ... -
Differentiating sensitivity of post-stimulus undershoot under diffusion weighting: implication of vascular and neuronal hierarchy.
(PLoS One, 2008-08-13)The widely used blood oxygenation level dependent (BOLD) signal during brain activation, as measured in typical fMRI methods, is composed of several distinct phases, the last of which, and perhaps the least understood, is ... -
Diffuse reduction of white matter connectivity in cerebral palsy with specific vulnerability of long range fiber tracts.
(NeuroImage. Clinical, 2013-01)Cerebral palsy (CP) is a heterogeneous group of non-progressive motor disorders caused by injury to the developing fetal or infant brain. Although the defining feature of CP is motor impairment, numerous other neurodevelopmental ... -
Diffusion tensor imaging of cerebral white matter integrity in cognitive aging.
(Biochimica et biophysica acta, 2012-03)In this article we review recent research on diffusion tensor imaging (DTI) of white matter (WM) integrity and the implications for age-related differences in cognition. Neurobiological mechanisms defined from DTI analyses ... -
Effect of Autologous Cord Blood Infusion on Motor Function and Brain Connectivity in Young Children with Cerebral Palsy: A Randomized, Placebo-Controlled Trial.
(Stem cells translational medicine, 2017-12)Cerebral palsy (CP) is a condition affecting young children that causes lifelong disabilities. Umbilical cord blood cells improve motor function in experimental systems via paracrine signaling. After demonstrating safety, ... -
Functional parcellation of attentional control regions of the brain.
(J Cogn Neurosci, 2004-01)Recently, a number of investigators have examined the neural loci of psychological processes enabling the control of visual spatial attention using cued-attention paradigms in combination with event-related functional magnetic ... -
Improved delineation of short cortical association fibers and gray/white matter boundary using whole-brain three-dimensional diffusion tensor imaging at submillimeter spatial resolution.
(Brain Connect, 2014-11)Recent emergence of human connectome imaging has led to a high demand on angular and spatial resolutions for diffusion magnetic resonance imaging (MRI). While there have been significant growths in high angular resolution ... -
Maintenance and Representation of Mind Wandering during Resting-State fMRI.
(Scientific reports, 2017-01-12)Major advances in resting-state functional magnetic resonance imaging (fMRI) techniques in the last two decades have provided a tool to better understand the functional organization of the brain both in health and illness. ... -
Preschool anxiety disorders predict different patterns of amygdala-prefrontal connectivity at school-age.
(PLoS One, 2015)OBJECTIVE: In this prospective, longitudinal study of young children, we examined whether a history of preschool generalized anxiety, separation anxiety, and/or social phobia is associated with amygdala-prefrontal dysregulation ...
