Browsing by Author "Spana, Eric P"
Now showing items 1-5 of 5
-
A paired-end sequencing strategy to map the complex landscape of transcription initiation.
(Nature methods, 2010-07)Recent studies using high-throughput sequencing protocols have uncovered the complexity of mammalian transcription by RNA polymerase II, helping to define several initiation patterns in which transcription start sites (TSSs) ... -
Characterization of the tilt (tt) phenotype in Drosophila melanogaster.
(microPublication biology, 2023-01)In the early 20th century, Calvin Bridges and Thomas Morgan identified a number of spontaneous mutations that displayed visible phenotypes in adult flies and subsequent analysis of these mutations over the past century have ... -
Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
(G3 (Bethesda, Md.), 2015-03-04)The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties impact the evolution ... -
speck, First Identified in Drosophila melanogaster in 1910, Is Encoded by the Arylalkalamine N-Acetyltransferase (AANAT1) Gene.
(G3 (Bethesda, Md.), 2020-09-02)The pigmentation mutation speck is a commonly used recombination marker characterized by a darkly pigmented region at the wing hinge. Identified in 1910 by Thomas Hunt Morgan, speck was characterized by Sturtevant as the ... -
Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element.
(G3 (Bethesda, Md.), 2017-08-07)The discordance between genome size and the complexity of eukaryotes can partly be attributed to differences in repeat density. The Muller F element (∼5.2 Mb) is the smallest chromosome in Drosophila melanogaster, but it ...
