Now showing items 1-3 of 3

    • EPR spectroscopy of nitrite complexes of methemoglobin. 

      Schwab, DE; Stamler, JS; Singel, DJ (Inorg Chem, 2010-07-19)
      The chemical interplay of nitrogen oxides (NO's) with hemoglobin (Hb) has attracted considerable recent attention because of its potential significance in the mechanism of NO-related vasoactivity regulated by Hb. An important ...
    • Fiber type-specific nitric oxide protects oxidative myofibers against cachectic stimuli. 

      Yu, Z; Li, P; Zhang, M; Hannink, M; Stamler, JS; Yan, Z (PLoS One, 2008-05-07)
      Oxidative skeletal muscles are more resistant than glycolytic muscles to cachexia caused by chronic heart failure and other chronic diseases. The molecular mechanism for the protection associated with oxidative phenotype ...
    • Pharmacologic Targeting of Red Blood Cells to Improve Tissue Oxygenation. 

      Farhan, O; Hess, DT; Jenkins, T; Longphre, JM; Matto, F; Moon, Richard Edward; Morris, N; ... (11 authors) (Clin Pharmacol Ther, 2017-12-14)
      Disruption of microvascular blood flow is a common cause of tissue hypoxia in disease, yet no therapies are available that directly target the microvasculature to improve tissue oxygenation. Red blood cells (RBCs) autoregulate ...