Now showing items 1-2 of 2

    • B-lymphocyte effector functions in health and disease. 

      DiLillo, DJ; Horikawa, M; Tedder, TF (Immunol Res, 2011-04)
      B-lymphocytes have traditionally been thought to contribute to immunity and autoimmune disease through terminal differentiation into plasma cells that secrete antibody. However, studies in mice and recent clinical studiees ...
    • CD20 deficiency in humans results in impaired T cell-independent antibody responses. 

      Kuijpers, TW; Bende, RJ; Baars, PA; Grummels, A; Derks, IAM; Dolman, KM; Beaumont, T; ... (11 authors) (J Clin Invest, 2010-01)
      CD20 was the first B cell differentiation antigen identified, and CD20-specific mAbs are commonly used for the treatment of B cell malignancies and autoantibody-mediated autoimmune diseases. Despite this the role of CD200 ...