Browsing by Author "Tomhave, ED"

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Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by beta-adrenergic receptor stimulation and blockade.

Iaccarino, G; Tomhave, ED; Lefkowitz, RJ; Koch, WJ (Circulation, 1998-10-27)

BACKGROUND: Impaired myocardial beta-adrenergic receptor (betaAR) signaling, including desensitization and functional uncoupling, is a characteristic of congestive heart failure. A contributing mechanism for this impairment ...