Browsing by Author "Van de Ven, Thomas"
Now showing items 1-5 of 5
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Differential expression of systemic inflammatory mediators in amputees with chronic residual limb pain.
(Pain, 2017-01)Chronic postsurgical pain impacts most amputees, with more than half experiencing neuralgic residual limb pain. The transition from normal acute postamputation pain to chronic residual limb pain likely involves both peripheral ... -
DNA methylation profiles are associated with complex regional pain syndrome after traumatic injury.
(Pain, 2019-10)Factors contributing to development of complex regional pain syndrome (CRPS) are not fully understood. This study examined possible epigenetic mechanisms that may contribute to CRPS after traumatic injury. DNA methylation ... -
Epigenetics and the transition from acute to chronic pain.
(Pain medicine (Malden, Mass.), 2012-11)The objective of this study was to review the epigenetic modifications involved in the transition from acute to chronic pain and to identify potential targets for the development of novel, individualized pain therapeutic... -
Pain Phenotypes and Associated Clinical Risk Factors Following Traumatic Amputation: Results from Veterans Integrated Pain Evaluation Research (VIPER).
(Pain medicine (Malden, Mass.), 2016-01)OBJECTIVE:To define clinical phenotypes of postamputation pain and identify markers of risk for the development of chronic pain. DESIGN:Cross-sectional study of military service members enrolled 3-18 months after traumatic ... -
The Impact of Surgical Amputation and Valproic Acid on Pain and Functional Trajectory: Results from the Veterans Integrated Pain Evaluation Research (VIPER) Randomized, Double-Blinded Placebo-Controlled Trial.
(Pain medicine (Malden, Mass.), 2019-05-02)OBJECTIVE:To determine if the perioperative administration of valproic acid reduces the incidence of chronic pain three months after amputation or revision surgery. DESIGN:Multicenter, randomized, double-blind, placebo-controlled ...
