Now showing items 1-3 of 3

    • COPD: balancing oxidants and antioxidants. 

      Fischer, Bernard Martin; Ghio, Andrew J; Voynow, JA (Int J Chron Obstruct Pulmon Dis, 2015)
      Chronic obstructive pulmonary disease (COPD) is one of the most common chronic illnesses in the world. The disease encompasses emphysema, chronic bronchitis, and small airway obstruction and can be caused by environmental ...
    • Deficiency of α-1-antitrypsin influences systemic iron homeostasis. 

      Fischer, Bernard Martin; Ghio, Andrew J; Richards, JH; Schmechel, DE; Soukup, JM; Voynow, JA (Int J Chron Obstruct Pulmon Dis, 2013)
      There is evidence that proteases and antiproteases participate in the iron homeostasis of cells and living systems. We tested the postulate that α-1 antitrypsin (A1AT) polymorphism and the consequent deficiency ...
    • Pathogenic triad in COPD: oxidative stress, protease-antiprotease imbalance, and inflammation. 

      Fischer, Bernard Martin; Pavlisko, Elizabeth N; Voynow, JA (Int J Chron Obstruct Pulmon Dis, 2011)
      Patients with chronic obstructive pulmonary disease (COPD) exhibit dominant features of chronic bronchitis, emphysema, and/or asthma, with a common phenotype of airflow obstruction. COPD pulmonary physiology reflects the ...