Browsing by Author "Wang, Hongyan"

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Deciphering and targeting host factors to counteract SARS-CoV-2 and coronavirus infections: insights from CRISPR approaches.

Cui, Zhifen; Wang, Hongyan; Dong, Yizhou; Liu, Shan-Lu; Wang, Qianben (Frontiers in genome editing, 2023-01)

Severe respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses depend on host factors for the process of viral infection and replication. A better understanding of the dynamic interplay between viral pathogens ...
Molecular determinants for enzalutamide-induced transcription in prostate cancer.

Yuan, Fuwen; Hankey, William; Wu, Dayong; Wang, Hongyan; Somarelli, Jason; Armstrong, Andrew J; Huang, Jiaoti; ... (9 authors) (Nucleic acids research, 2019-11)

Enzalutamide, a second-generation androgen receptor (AR) antagonist, has demonstrated clinical benefit in men with prostate cancer. However, it only provides a temporary response and modest increase in survival, indicating ...