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Browsing by Author "Wang, L"
Now showing items 1-15 of 15
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Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using SILAC-based quantitative proteomics.
Yang, W; Thompson, JW; Wang, Z; Wang, L; Sheng, H; Foster, MW; Moseley, MA; ... (8 authors) (Journal of proteome research, 2012-02)Transient cerebral ischemia dramatically activates small ubiquitin-like modifier (SUMO2/3) conjugation. In cells exposed to 6 h of transient oxygen/glucose deprivation (OGD), a model of ischemia, SUMOylation increases profoundly ... -
Complexity of randomized algorithms for underdamped Langevin dynamics
Cao, Y; Lu, J; Wang, LWe establish an information complexity lower bound of randomized algorithms for simulating underdamped Langevin dynamics. More specifically, we prove that the worst $L^2$ strong error is of order $\Omega(\sqrt{d}\, N^{-3/2})$, ... -
CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation.
Wang, L; Oehlers, SH; Espenschied, ST; Rawls, JF; Tobin, DM; Ko, DC (Genome Biol, 2015-09-15)Meta-analyses of genome-wide association studies (GWAS) have demonstrated that the same genetic variants can be associated with multiple diseases and other complex traits. We present software called CPAG (Cross-Phenotype ... -
Cross-cultural differences of the non-motor symptoms studied by the traditional Chinese version of the International Parkinson and Movement Disorder Society–unified Parkinson’s disease rating scale
Yu, RL; Wu, RM; Chan, AYY; Mok, V; Wu, YR; Tilley, BC; Luo, S; ... (11 authors) (Movement Disorders Clinical Practice, 2017) -
Gender-, age-, and race/ethnicity-based differential item functioning analysis of the movement disorder society–sponsored revision of the Unified Parkinson’s disease rating scale
Goetz, CG; Liu, Y; Stebbins, GT; Wang, L; Tilley, BC; Teresi, JA; Merkitch, D; ... (8 authors) (Movement Disorders, 2016) -
Generalized Bregman Divergence and Gradient of Mutual Information for Vector Poisson Channels
Wang, L; Rodrigues, M; Carin, L (2013 IEEE INTERNATIONAL SYMPOSIUM ON INFORMATION THEORY PROCEEDINGS (ISIT), 2013) -
Handling missing values in the MDS-UPDRS
Goetz, CG; Luo, S; Wang, L; Tilley, BC; LaPelle, NR; Stebbins, GT (Movement Disorders, 2015) -
Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis
Wang, L; Ko, ER; Gilchrist, JJ; Pittman, KJ; Rautanen, A; Pirinen, M; Thompson, JW; ... (23 authors) (Science Advances, 2017-03-08)Sepsis is a deleterious inflammatory response to infection with high mortality. Reliable sepsis biomarkers could improve diagnosis, prognosis, and treatment. Integration of human genetics, patient metabolite and cytokine ... -
Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol
Alvarez, MI; Glover, LC; Luo, P; Wang, L; Theusch, E; Oehlers, SH; Walton, EM; ... (16 authors) (Proceedings of the National Academy of Sciences, 2017-08-21)Risk, severity, and outcome of infection depend on the interplay of pathogen virulence and host susceptibility. Systematic identification of genetic susceptibility to infection is being undertaken through genome-wide association ... -
Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture.
Moore, AB; Yu, L; Swartz, CD; Zheng, X; Wang, L; Castro, L; Kissling, GE; ... (10 authors) (Cell Commun Signal, 2010-06-10)BACKGROUND: Uterine leiomyomas (fibroids) are benign smooth muscle tumors that often contain an excessive extracellular matrix (ECM). In the present study, we investigated the interactions between human uterine leiomyoma ... -
Independent Spanish validation of the Unified Dyskinesia rating scale
Cubo, E; Goetz, CG; Stebbins, GT; LaPelle, NR; Tilley, BC; Wang, L; Luo, S (Movement Disorders Clinical Practice, 2014) -
MDS-sponsored scale translation program: process, format, and clinimetric testing plan for the MDS-UPDRS and UDysRS
Goetz, CG; Stebbins, GT; Wang, L; LaPelle, NR; Luo, S; Tilley, BC (Movement Disorders Clinical Practice, 2014) -
Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis.
Shah, SH; Freedman, NJ; Zhang, L; Crosslin, DR; Stone, DH; Haynes, C; Johnson, J; ... (22 authors) (PLoS Genet, 2009-01)Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease (CAD). We have previously identified genetic linkage to familial CAD in the genomic region of NPY. We performed follow-up genetic, biostatistical, ... -
Numerical methods for stochastic differential equations based on Gaussian mixture
Li, L; Lu, J; Mattingly, JC; Wang, LWe develop in this work a numerical method for stochastic differential equations (SDEs) with weak second order accuracy based on Gaussian mixture. Unlike the conventional higher order schemes for SDEs based on It\^o-Tayl... -
Official Japanese version of the Movement Disorder Society-unified Parkinson's disease rating scale: validation against the original English version
Kashihara, K; Tomoyoshi, T; Mizuno, Y; Kikuchi, S; Kuno, S; Hasegawa, K; Hattori, N; ... (24 authors) (Movement Disorders Clinical Practice, 2014)