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Browsing by Author "Wang, L"
Now showing items 1-15 of 15
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Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using SILAC-based quantitative proteomics.
(Journal of proteome research, 2012-02)Transient cerebral ischemia dramatically activates small ubiquitin-like modifier (SUMO2/3) conjugation. In cells exposed to 6 h of transient oxygen/glucose deprivation (OGD), a model of ischemia, SUMOylation increases profoundly ... -
Complexity of randomized algorithms for underdamped Langevin dynamics
We establish an information complexity lower bound of randomized algorithms for simulating underdamped Langevin dynamics. More specifically, we prove that the worst $L^2$ strong error is of order $\Omega(\sqrt{d}\, N^{-3/2})$, ... -
CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation.
(Genome Biol, 2015-09-15)Meta-analyses of genome-wide association studies (GWAS) have demonstrated that the same genetic variants can be associated with multiple diseases and other complex traits. We present software called CPAG (Cross-Phenotype ... -
Generalized Bregman Divergence and Gradient of Mutual Information for Vector Poisson Channels
(2013 IEEE INTERNATIONAL SYMPOSIUM ON INFORMATION THEORY PROCEEDINGS (ISIT), 2013) -
Handling missing values in the MDS-UPDRS
(Movement Disorders, 2015) -
Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis
(Science Advances, 2017-03-08)Sepsis is a deleterious inflammatory response to infection with high mortality. Reliable sepsis biomarkers could improve diagnosis, prognosis, and treatment. Integration of human genetics, patient metabolite and cytokine ... -
Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol
(Proceedings of the National Academy of Sciences, 2017-08-21)Risk, severity, and outcome of infection depend on the interplay of pathogen virulence and host susceptibility. Systematic identification of genetic susceptibility to infection is being undertaken through genome-wide association ... -
Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture.
(Cell Commun Signal, 2010-06-10)BACKGROUND: Uterine leiomyomas (fibroids) are benign smooth muscle tumors that often contain an excessive extracellular matrix (ECM). In the present study, we investigated the interactions between human uterine leiomyoma ... -
Independent Spanish validation of the Unified Dyskinesia rating scale
(Movement Disorders Clinical Practice, 2014) -
MDS-sponsored scale translation program: process, format, and clinimetric testing plan for the MDS-UPDRS and UDysRS
(Movement Disorders Clinical Practice, 2014) -
Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis.
(PLoS Genet, 2009-01)Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease (CAD). We have previously identified genetic linkage to familial CAD in the genomic region of NPY. We performed follow-up genetic, biostatistical, ... -
Numerical methods for stochastic differential equations based on Gaussian mixture
We develop in this work a numerical method for stochastic differential equations (SDEs) with weak second order accuracy based on Gaussian mixture. Unlike the conventional higher order schemes for SDEs based on It\^o-Tayl... -
Official Japanese version of the Movement Disorder Society-unified Parkinson's disease rating scale: validation against the original English version
(Movement Disorders Clinical Practice, 2014)
