Now showing items 1-2 of 2

    • Detectable clonal mosaicism from birth to old age and its relationship to cancer. 

      Laurie, Cathy C; Laurie, Cecelia A; Rice, Kenneth; Doheny, Kimberly F; Zelnick, Leila R; McHugh, Caitlin P; Ling, Hua; ... (73 authors) (Nature genetics, 2012-05-06)
      We detected clonal mosaicism for large chromosomal anomalies (duplications, deletions and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited for genome-wide association studies. This detection ...
    • Joint effect of multiple common SNPs predicts melanoma susceptibility. 

      Fang, Shenying; Han, Jiali; Zhang, Mingfeng; Wang, Li-e; Wei, Qingyi; Amos, Christopher I; Lee, Jeffrey E (PloS one, 2013-01)
      Single genetic variants discovered so far have been only weakly associated with melanoma. This study aims to use multiple single nucleotide polymorphisms (SNPs) jointly to obtain a larger genetic effect and to improve the ...